RATIONAL PHARMACOTHERAPY FOR UPPER RESPIRATORY TRACT INFECTIONS: THE ABILITIES OF IMMUNAL
- Authors: Morozova T.1, Rykova S.1
-
Affiliations:
- I.M. Sechenov First Moscow State Medical University
- Issue: Vol 24, No 3 (2013)
- Pages: 20-24
- Section: Articles
- URL: https://journals.eco-vector.com/0236-3054/article/view/115648
- ID: 115648
Cite item
Open Access
Access granted
Abstract
Acute respiratory viral infections (ARVI) belong to the most common illnesses in both adults and children. Not only ENT physicians, but also, first of all, therapists and pediatricians encounter them in the outpatient setting. The paper provides an evidence-based review of Immunal®. Russian and international experience with the drug based on Echinacea, including that in combination with ascorbic acid, suggests its high efficacy as an immunomodulator and its good safely profile when used in the combination therapy for ARVI.
Full Text
About the authors
T. Morozova
I.M. Sechenov First Moscow State Medical University
Email: temorozova@gmail.com
S. Rykova
I.M. Sechenov First Moscow State Medical University
References
- Василевский И.В. Часто болеющие дети: практические подходы к иммунокорригирующей терапии / Медицина, 2008; 2: 93-9.
- Ерофеев М.К., Максакова М.А., Шадрин А.С. Оценка эффективности применения препарата Иммунал с целью профилактики гриппа и других острых респираторных заболеваний // Terra medica. - 2000; 4 (20): 379-81.
- Латышева Т.В., Медуницына Е.Н. Иммунал и его применение при инфекционных заболеваниях респираторного тракта, кожи и слизистых // Рус. мед. журн. - 2005; 13 (21): 1383-5.
- Лусс Л.В. Место иммуномодуляторов в педиатрической практике Consilium Мedicum (Прил. Педиатрия). - 2010; 3: 72-6.
- Маркова Т.П. Растительный иммуностимулирующий препарат -Иммунал. Перспективы применения в медицине // Рус. мед. журн. - 2002; 10 (28) URL: http://www.rmj.ru/articles1200.htm
- Романцов М.Г., Ершов Ф.И. Часто болеющие дети: современная фармакотерапия. ИГ ГЭОТАР-Медиа. - М.: 2006; с. 191.
- Сенцова Т.Б. Иммуномодуляторы в общеврачебной практике // Consilium Мedicum. - 2006; 8 (10): 25-30.
- Царев С.В. Эффективность Иммунала как неспецифического иммуностимулятора // Рос. мед. журн. - 2003; 11 (16): 950-3.
- Douglas R., Hemila H., D’Souza R. et al. Vitamin C for preventing and treating the common cold. Cochrane Database Systematic Reviews. - 2004; 18 (4): CD000980.
- Foster S. Echinacea Natures immune Enchancer Rochester. Vermount, 1990; 150 p.
- Goel V., Efficacy of a standardized echinacea preparation (EchinilinTM) for the treatment of the common cold: a randomized, double-blind, placebo-controlled trial // J. Clin. Pharm. Ther. - 2004; 29, 75-83.
- Grimm W., Muller H. A randomized controlled trial of the effect of fluid extract of Echinacea purpurea of the incidence and severity of colds and respiratory infections // Am. J. Med. - 1999; 106 (2): 138-43.
- Hoheisel O. et al. Echinagard treatment shortens the course of the common cold: double blind, placebo controlled clinical trial // Eur. J. Clin. Res. - 1997; 9: 261-8.
- Huntley A., Thompson С., Ernst E. The safety of herbal medicinal products derived from Echinacea species: a systematic review // Drug. Saf. - 2005; 28 (5): 387-400.
- Linde K., Barrett B., Wolkart K. et al. Echinacea for preventingand treating the common cold // Cochrane Database Syst. Rev. - 2006; 25 (1): CD000530.
- Maggini S. Essential Role of Vitamin C and Zinc in Child Immunity and Health // J. Internat. Med.Research. - 2010; 38: 386-414.
- Parnham M. Benefit - risk assessment of the squeezed sap the purple coneflower (Echinacea purpurea) for long-term oral immunostimulation // Phytomedicine. - 1996; 3 (1): 95-102.
- Perri D., Dugoua J.-J., Mills E. et al. Safety and efficacy of echinacea (Echinacea angustafolia, e. purpurea and e. pallida) during pregnancy and lactation // Can. J. Clin. Pharm. - 2006; 13 (3): 262-7.
- Schoop R., Klein P., Suter A. et al. Echinacea in the prevention of induced rhinovirus colds: a meta-analysis // Clin. Ther. - 2006; 28 (2): 174-83.
- Schulten B., Bulitta M., Brigitta B. et al. Efficacy of Echinacea purpurea in patients with a common cold: a placebo-controlled, randomised, double-blind clinical trial // Arzneimittelforschung. - 2001; 51: 563-8.
- Shah S., Sander S., White C. et al. Evaluation of Echinacea for the prevention and treatment of the common cold: a meta-analysis // Lancet Infect. Dis. - 2007; 7 (7): 473-80.
- Stotzem C., Hangerland U., Mengs U. Influence of Echinacea purpurea on the phagocetosis of human granulocytes // Med. Sci. Res. - 1992; 20: 719-20.
- Surcic K., Melchart D., Holzmann M. Zwei Probandenstudien zur Stimulierung der Granulozyten - phagozitose durch echinaceaextracthaltige Praparate // Z. Phutother. - 1989; 10: 67-70.
- Taylor J., Weber W., Standish L. et al. Efficacy and safety of echinacea in treating upper respiratory tract infections in children: a randomized controlled trial // JAMA. - 2003; 290 (21): 2824-30.
Supplementary files
