ROLE OF [-2]proPSA AND ITS DERIVATIVES IN PROSTATE CANCER SCREENING IN MEN WITH A TOTAL PROSTATE-SPECIFIC ANTIGEN LEVEL OF 2-10 NG/ML
- Authors: Nevirovich E.1, Yakovenko A.1, Rumyantsev A.1, Budylev S.2, Selivanov A.2
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Affiliations:
- Acad. I.P. Pavlov First Saint Petersburg State Medical University
- City Hospital Thirty-One
- Issue: Vol 26, No 6 (2015)
- Pages: 63-65
- Section: Articles
- URL: https://journals.eco-vector.com/0236-3054/article/view/116334
- ID: 116334
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Abstract
The efficiency of using [-2]proPSA and its derivative a p2PSA to free prostate-specific antigen (PSA) ratio (%p2PSA) for the early detection of prostate cancer in men with a total prostate-specific antigen level of 2 to 10 ng/ml.
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About the authors
E. Nevirovich
Acad. I.P. Pavlov First Saint Petersburg State Medical University
A. Yakovenko
Acad. I.P. Pavlov First Saint Petersburg State Medical University
A. Rumyantsev
Acad. I.P. Pavlov First Saint Petersburg State Medical University
S. Budylev
City Hospital Thirty-OneSaint Petersburg
A. Selivanov
City Hospital Thirty-OneSaint Petersburg
References
- Siddiqui M., Rais-Bahrami S., Turkbey B. et al. Comparison of MR/ultrasound fusion-guided biopsy with ultrasound-guided biopsy for the diagnosis of prostate cancer // JAMA. - 2015; 313 (4): 390-7.
- Siegel R., Naishadman D., Jemal A. Cancer statistics, 2013 // CA Cancer J. Clin. - 2013; 63 (1): 11-30.
- Schroder F., Hugosson J., Roobol M. et al. Screening and prostate cancer mortality: results of the European Randomised Study of Screening for Prostate Cancer (ERSPC) at 13 years of follow-up // Lancet. - 2014; 384 (9959): 2027-35.
- Le B., Griffin C., Loeb S. et al. [-2] Proenzyme prostate specific antigen is more accurate than total and free prostate specific antigen in differentiating prostate cancer from benign disease in a prospective prostate cancer screening study // J. Urol. - 2010; 183 (4): 1355-9.
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