ROLE OF [-2]proPSA AND ITS DERIVATIVES IN PROSTATE CANCER SCREENING IN MEN WITH A TOTAL PROSTATE-SPECIFIC ANTIGEN LEVEL OF 2-10 NG/ML


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详细

The efficiency of using [-2]proPSA and its derivative a p2PSA to free prostate-specific antigen (PSA) ratio (%p2PSA) for the early detection of prostate cancer in men with a total prostate-specific antigen level of 2 to 10 ng/ml.

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作者简介

E. Nevirovich

Acad. I.P. Pavlov First Saint Petersburg State Medical University

A. Yakovenko

Acad. I.P. Pavlov First Saint Petersburg State Medical University

A. Rumyantsev

Acad. I.P. Pavlov First Saint Petersburg State Medical University

S. Budylev

City Hospital Thirty-One

Saint Petersburg

A. Selivanov

City Hospital Thirty-One

Saint Petersburg

参考

  1. Siddiqui M., Rais-Bahrami S., Turkbey B. et al. Comparison of MR/ultrasound fusion-guided biopsy with ultrasound-guided biopsy for the diagnosis of prostate cancer // JAMA. - 2015; 313 (4): 390-7.
  2. Siegel R., Naishadman D., Jemal A. Cancer statistics, 2013 // CA Cancer J. Clin. - 2013; 63 (1): 11-30.
  3. Schroder F., Hugosson J., Roobol M. et al. Screening and prostate cancer mortality: results of the European Randomised Study of Screening for Prostate Cancer (ERSPC) at 13 years of follow-up // Lancet. - 2014; 384 (9959): 2027-35.
  4. Le B., Griffin C., Loeb S. et al. [-2] Proenzyme prostate specific antigen is more accurate than total and free prostate specific antigen in differentiating prostate cancer from benign disease in a prospective prostate cancer screening study // J. Urol. - 2010; 183 (4): 1355-9.

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