Vol 27, No 6 (2016)

The paper considers the problem of hypoglycemia in geriatric practice. According to clinical and experimental findings, hypoglycemia may contribute to maladaptive behavior and cognitive impairments and increase cardiovascular risk.

The paper considers the anatomy and physiology of the nociceptive sensory system in the context of age-related changes that determine the clinical features of acute pain syndrome. It analyzes problems in the diagnosis of acute pain, systematizes and generalizes its causes, and proposes approaches when rendering care for elderly patients.

The paper considers whether proximal femur fractures may be prevented by prophylactic bone augmentation with original implants in elderly patients with different diseases causing bone dystrophic changes and pathological fractures. The bed tests have indicated that in this case the stress in critical points increases by 11.6-12.1%; the strength of a bone-implant system in low-energy trauma rises by 23-93%.

The paper considers the problems of falls in elderly and senile patients, their etiology and pathogenesis, a risk for falls, and issues of their prevention and complications.

The paper describes the properties of saffron (Crocus sativus L.) that may be considered as a potential anti-aging phytoprotective agent for metabolic syndrome (MS). Addition of anti-aging agents to basic therapy for MS is pathogenetically sound. Saffron as a potential anti-aging agent is shown to be able to affect body weight, lipid profile, and sexual function and, having moderate anorectic properties, may act as an aphrodisiac. Since saffron contains natural hormones, such as phytosterols, it may promote neurohumoral system stabilization, manifesting itself as optimization of lipid metabolic parameters and its related increase in sexual activity.

Longevity has been established to be typified by a high ability to work, a peculiar psychological personality pattern, preserved self-care capacity, and economic independence.

The paper gives the results of a prospective comparative study of different treatments (standard therapy and standard therapy in combination with a butyric acid preparation) in patients with irritable bowel syndrome (IBS). The study has demonstrated that the use of butyric acid in combination with standard therapy enhances the efficiency of therapy for pain syndrome and allows diarrhea control in patients with IBS.

Phlegmon of the retroperitoneal fat is its acute pyoinflammatory process that does not tend to delimit from intact tissues. The Department of Urology, Krasnoyarsk Interdistrict Clinical Hospital Four, annually encounters as many as 3 cases of retroperitoneal phlegmon. The clinical symptoms of retroperitoneal fat empyemas vary, which determines diagnostic difficulties. The paper describes a case of a senile patient with kidney destruction and retroperitoneal phlegmon with tumor involvement in the clinical picture of peritonitis.

The specific features of cardiac rhythm and conduction disturbances were identified in people from old age groups. The main areas of antiarrhythmic therapy for these conditions in elderly patients and a risk of adding some antiarrhythmic drugs were considered.

The paper shows a reduction in morbidity rates among the workers of OOO “Gazprom Urengoy Production" who work under poor climatic and environmental conditions, by using a personified procedure for molecular genetic testing, followed by peptide bioregulation of detected abnormalities.

Combination treatment for chronic generalized periodontitis has been optimized using bioregulatory therapy in elderly and senile patients.

Chronic diffuse viral liver diseases are characterized by common carotid artery remodeling with the decreased elasticity and increased stiffness of the vascular wall. More significant structural and functional changes are found in patients with chronic viral hepatitis.

Patients with Crohn’s disease (CD) have been found to have endothelial dysfunction that is characterized by increases in the level of serum vascular endothelial factor (VEF) and in that of plasma desquamated endotheliocytes (DEC). The levels of VEF and DEC may act as criteria for the severity of CD and as signs of its poor course.

The paper considers the main stages of development of the history of medicine as an independent scientific discipline in Russia and the contribution of Russian scientists to current systems ideas about it.