RADIATION THERAPY IN THE TREATMENT OF NON-SMALL-CELL LUNG CANCER
- Authors: Gogolln D.1, Gulidov I.1, Ragulln Y.1
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Affiliations:
- A.F. Tsyb Medical Radiology Research Center, Branch, National Medical RadiologyResearch Center, Ministry of Health of the Russian Federation
- Issue: Vol 27, No 2 (2016)
- Pages: 46-48
- Section: Articles
- URL: https://journals.eco-vector.com/0236-3054/article/view/116552
- ID: 116552
Cite item
Abstract
The paper considers the importance of radiotherapy in the combination treatment of patients with non-small-cell lung cancer (NSCLC). It describes different radiotherapy options and possibilities of combined treatments in patients with NSCLC.
Keywords
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About the authors
D. Gogolln
A.F. Tsyb Medical Radiology Research Center, Branch, National Medical RadiologyResearch Center, Ministry of Health of the Russian Federation
Email: dgogolin@yandex.ru
I. Gulidov
A.F. Tsyb Medical Radiology Research Center, Branch, National Medical RadiologyResearch Center, Ministry of Health of the Russian FederationMD; Professor
Yu. Ragulln
A.F. Tsyb Medical Radiology Research Center, Branch, National Medical RadiologyResearch Center, Ministry of Health of the Russian FederationCandidate of Medical Sciences
References
- http://globocan.iarc.fr/Pages/fact_sheets_cancer.aspx
- Давыдов М.И., Аксель Е.М. Статистика злокачественных новообразований в России и странах СНГ в 2010 г. / М.: РОНЦ, 2012.
- Злокачественные новообразования в России в 2013 году. Под ред. А.Д. Каприна, В.В. Старинского, Г.В. Петровой / М.: МНИОИ им. П.А. Герцена -филиал ФГБУ «ФМИЦ им. П.А. Герцена» Минздрава России, 2015; 250 с.
- Review on the tolerance of normal tissue to the therapeutic radiation // Int. J. Radiat. Oncol. Biol. Phys. - 2010; 76 (3): 1-120.
- Bral S., Gevaert T., Linthout N. et al. Prospective, risk-adapted strategy of stereotactic body radiotherapy for early-stage non-small-cell lung cancer: results of Phase II trial // Int. J. Rad. Oncol. Biol. Phys. - 2011; 80: 1314-49.
- Sashendra S., Haasbeek C., Slotman B. et al. Outcomes of stereotactic ablative radiotherapy for central lung tumors: A systematic review // Radioth. Oncol. - 2013; 106: 276-82.
- Бойко А.В., Черниченко А.В., Мещерякова И.А. и др. Лучевая терапия немелкоклеточного рака // Практ. онкол. - 2000; 3: 24-8.
- Cerfolio R., Bryant A., Cerfolio R. Pulmonary resection after concurrent chemotherapy and high dose (60 Gy) radiation for non-small cell lung cancer is safe and may provide increased survival // Eur. J. Cardiothorac. Surg. - 2009; 35 (4): 718-23.
- Kwong K., Edelman M., Suntharalingam M. et all. High-dose radiotherapy in trimodality treatment of Pancoast tumors results in high pathologic complete response rates and excellent long-term survival // J. Thorac. Cardiovasc. Surg. -2005; 129 (6): 1250-7.
- Воробьев А.В., Завьялов А.А., Добродеев А.Ю. и др. Комбинированное лечение рака легкого III стадией с интраоперационной лучевой терапией и радиосенсибилизацией // Сиб. онкол. журн. - 2009; Прил. 1: 75-6.
- Bradley J., Paulus R., Graham M. et al. Phase II trial of postoperative adjuvant paclitaxel/carboplatin and thoracic radiotherapy in resected stage II and IIIA non-small-cell lung cancer: promising long-term results of the Radiation Therapy Oncology Group - RTOG 9705 // J. Clin. Oncol. - 2005; 23 (15): 3480-7.
- Auperin A., Rolland E., Curran W. et al. Concomitant radiochemotherapy (RT-CT) versus sequential RT-CT in locally advanced non-small cell lung cancer (NSCLC): A meta-analysis using individual patient data (IPD) from randomized clinical trials (RCTs) // J. Thorac. Oncol. - 2007; 2: 310.
- Belderbos J., Uitterhoeve L., Belderbos H. et al. Randomised trial of sequential versus concurrent chemo-radiotherapy in patients with inoperable non-small cell lung cancer (EORTC 08972-22973) // Eur. J. Cancer. - 2007; 43: 114-21.
- Saunders M., Dische S., Barrett A. et al. Continuous hyperfractionated accelerated radiotherapy (CHART) versus conventional radiotherapy in non-small cell lung cancer: mature data from the randomised multicentre trial // Radioth. Oncol. - 1999; 52: 137-48.
- Belani C., Wang W., Johnson D. et al. Phase III study of the Eastern Cooperative Oncology Group (ECOG 2597): induction chemotherapy followed by either standard thoracic radiotherapy or hyperfractionated accelerated radiotherapy for patients with unresectable stage IIIA and B non-small-cell lung cancer // J. Clinic. Oncol. - 2005; 23 (16): 3760-7.
- Jeremic B., Milicic B., Milisavljevic S. Clinical prognostic factors in patients with locally advanced (stage III) non-small cell lung cancer treated with hyperfractionated radiation therapy with and without concurrent chemotherapy: single-Institution Experience in 600 patients // Cancer. - 2011; 117: 2995 -3003.
- Немкова Е.В., Мусс В.Ф. Лучевая терапия рака легкого с использованием методики нетрадиционного фракционирования и радиомодификации. Материалы Невского радиологического форума «Невские горизонты» / СПб, 2007; с. 680.
- Ильин М.А., Сотников В.М., Паньшин Г.А. и др. Результаты лучевой терапии немелкоклеточного рака легкого средними фракциями. Материалы IV Всеросс. нац. конгресса лучевых диагностов и терапевтов «Радиология-2010», 2010; с. 176.
- Гоголин Д.В., Гулидов И.А., Мардынский Ю.С. и др. Ускоренное гиперфракционирование с неравномерным дроблением дневной дозы при лучевом и химиолучевом лечении неоперабельного немелкоклеточного рака легкого // Сиб. онкол. журн. - 2014; 6: 5-9.
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