DETERMINANTS OF A RISK FOR CHRONIC KIDNEY DISEASE IN DIABETES MELLITUS


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详细

The influence of genetic factors on the risk of chronic kidney disease (CKD) was evaluated in patients with type 2 diabetes mellitus. A significant association was found between CKD and polymorphism of the genes (the products of which play a decisive role in the pathogenesis of renal injury) encoding the production of endothelial vasoactive factors (NOS34 gene) and lipid metabolism factors (APOB gene).

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作者简介

O. Vikulova

Endocrinology Research Center, Moscow

Candidate of Medical Sciences

A. Zheleznyakova

Endocrinology Research Center, Moscow

Email: azhelez@gmail.com

V. Nosikov

GosNII Gentika State Genetics Research Center

M. Shestakova

Endocrinology Research Center, Moscow

参考

  1. Викулова O.K. Клинико-лабораторные и генетические факторы развития и прогрессирования диабетической нефропатии у больных сахарным диабетом 1 типа. Автореф. дис.. канд. мед. наук. М., 2003.
  2. Железнякова А.В., Викулова О.К., Носиков В.В. и др. Генетические факторы развития хронической болезни почек у больных сахарным диабетом 2 типа // Теор. и практ. соврем. науки. - 2012; 2: 364-8.
  3. Шестакова М.В., Дедов И.И. Сахарный диабет и хроническая болезнь почек. М., 2009.
  4. Hajhosseiny R., Khavandi K., Goldsmith D. Cardiovascular disease in chronic kidney disease: untying the Gordian knot // Int. J. Clin. Pract. - 2013; 67 (1): 14-31.
  5. Johns M. (Jr), Paulus-Thomas J. Purification of human genomic DNA from whole blood using sodium perchlorate in place of phenol // Anal. Biochem. - 1989; 180 (2): 276-8.
  6. KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease // Kidney Int. Suppl. - 2013; 3 (1): 1-150.
  7. Noiri E., Satoh H., Taguchi J. et al. Association of eNOS Glu298Asp polymorphism with end-stage renal disease // Hypertension. - 2002; 40 (4): 535-40.
  8. Shestakova M., Vikulova O., Gorashko N. et al. The relationship between genetic and haemodynamic factors in diabetic nephropathy (DN): Case-control study in type 1 diabetes mellitus (T1DM) // Diabet. Res. Clin. Pract. - 2006; 74 (2): 41-50.
  9. Wang Y., Kikuchi S., Suzuki H. et al. Endothelial nitric oxide synthase gene polymorphism in intron 4 affects the progression of renal failure in non-diabetic renal diseases // Nephrol. Dial. Transplant. - 1999; 14 (12): 2898-902.
  10. Zintzaras E., Papathanasiou A., Stefanidis I. Endothelial nitric oxide synthase gene polymorphisms and diabetic nephropathy: a HuGE review and metaanalysis // Genet. Med. - 2009; 11 (10): 695-706.

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