卷 29, 编号 2 (2018)

The paper considers the actual problem of modern occupational medicine, pulmonology, and oncology, such as occupational lung cancer. It describes leading carcinogenic factors and production processes, which lead to its development.

The paper considers the presumed mechanisms of the etiology and pathogenesis of a common skin disease, such as atopic dermatitis (AD), from the point of view of psychosomatic theories and models in modern medicine. It analyzes the literature data suggesting that the peptidergic and immune systems are actively involved in the development of key symptoms of the disease. The systems of monoamine neurotransmitters (dopamine, noradrenaline, and serotonin) participating in the development and functioning of all mental processes (emotions, thinking, perception, etc.) were found to also play an important role in the pathogenesis of AD. There are examples of successfully using drugs from the groups of neuroleptics, antidepressants, tranquilizers in AT.

Cervical cancer (CC) occupies one of the leading positions in the structure of gynecological cancer morbidity and mortality, by attracting the special attention of rehabilitation physicians. Medical rehabilitation is an essential component of the therapeutic process in modern gynecological oncology, which allows the epidemiological situation of CC to be improved

The paper presents the results of investigating the efficacy of bioregulatory drugs in the combination treatment of patients with varying severity of chronic obstructive pulmonary disease (COPD) concurrent with coronary heart disease (CHD). Estimation of inflammation markers in sputum, bronchial lavages, and serum, such as interleukin (IL)-8, tumor necrosis factor-а, interferon-y, IL-10, and C-reactive protein before and after treatment revealed the good anti-inflammatory effect of the bioregulatory drugs. Their incorporation into conventional treatment regimens for COPD and CHD can enhance the efficiency of treatment and improve quality of life in patients.

The authors have investigated the correlations between clinical, biochemical, metabolic, vascular inflammatory, and molecular genetic parameters and the development of recurrent ischemic stroke; a prognostic model for determining the probability of its occurrence has been constructed.

The paper shows height trends in 118 children who are treated with dialysis and have undergone kidney transplantation. At the start of renal replacement treatment, the height standard deviation scores (SDS) in the patients were -1.16±1.74 with a need for growth hormone therapy in 28%.

The paper describes a case of development of hypertensive leg ulcers (Martorell’s ulcers) in a male patient who has been suffering from essential hypertension for many years. Wound healing could be achieved after selecting antihypertensive therapy and performing a stepwise dermatoplasty. The paper provides a brief review of the literature.

The paper gives the results of an investigation estimating the contribution of metabolically healthy obesity to the remodeling of the vascular wall and the functional state of the endothelium in young hypertensive women with estrogen deficiency.

Lateralization of the neotympanic membrane can be diagnosed even a few years after middle ear surgery. The paper considers the issues of its surgical treatment.

A comparison of sexual behavior models among men having sex with men and heterosexual men shows the need for first additional preventive and diagnostic measures to control the spread of sexually transmitted infections.

Some aspects of professional activities in polyclinic physicians in the healthcare reform period were investigated. A sociological survey was conducted using a questionnaire consisting of several conceptual domains: respondents’ sociodemographic characteristics; evaluation of production factors and various aspects of physicians’ professional activities; and estimation of satisfaction of physicians with their work.

The use of bioregulatory drugs contributes to positive changes in the postural and motor activities of patients with infantile cerebral paralysis and improves the central nervous, neuromuscular, and locomotor systems.