DIFFERENTIAL DIAGNOSIS OF BENIGN, BORDERLINE, AND MALIGNANT OVARIAN MASSES IN PREGNANT WOMEN, BY USING LOGISTIC REGRESSION MODELS


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Abstract

Objective. To enhance the accuracy of differential diagnosis of benign, borderline, and malignant ovarian tumors in pregnant women, by building a logistic regression model. Material and methods. Regression logistic models were built to demonstrate that one can differentiate true tumors from tumor-like masses and benign neoplasms from malignant ones in 223 pregnant women on the basis of ultrasound signs of ovarian tumor-like masses and tumors. Results. While diagnosing benign ovarian tumors in pregnant women, the sensitivity and specificity of the model were 97 and 95%, respectively. While diagnosing borderline and malignant tumors, the sensitivity of the model was 100% and its specificity was 92.3% with a total accuracy of 92.8%. Conclusion. The performed studies have demonstrated that the authors’ regression logistic models can help a practitioner make timely a differential diagnosis of ovarian tumors in pregnant women, thus using their rational treatment policy.

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About the authors

A. A GERASIMOVA

Center for Family Planning and Reproduction, Moscow Healthcare Department

Moscow

S. L SHVYREV

Russian State Medical University, Russian Agency for Health Care

Moscow

K. I STEPANOV

Russian State Medical University, Russian Agency for Health Care

Moscow

A. I GUS

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia

Moscow

P. A KLIMENKO

Russian State Medical University, Russian Agency for Health Care

Moscow

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