ANALYSIS OF THE MANAGEMENT OF PRETERM LABOR THAT ENDS WITH THE BIRTH OF EXTREMELY LOW BIRTH WEIGHT BABIES: THE FIRST EXPERIENCE IN THE ERA OF NEW LIVE BIRTH CRITERIA


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Objective. To estimate tactics for the management of very early preterm labor and the perinatal outcomes of extremely low birth weight (ELBW) babies. Subject and methods. The investigation included all infants born with an ELBW of less than 1000 g in 2012. In this period, a total of 64 ELBW babies were born. They were conventionally divided into 2 groups: 1) 44 survivors; 2) 20 dead infants. Maternal age, parity, duration of pregnancy at delivery, babies’ birthweight, causes of preterm labor, mode of delivery, fetal presentation, the number of fetuses, and type of chorionicity in multiple pregnancy were analyzed. Results. The investigation indicated that Group 2 mothers had a history of obstetric and gynecological diseases in 90% of cases. The babies weighing less than 500 g had the highest mortality rates (66.7%). The main cause of preterm labor was decompensated chronic fetoplacental insufficiency in Group 1 (38.6%) and premature amniorrhea and chorioamnionitis in Group 2 (55%). The critical period for survival of ELBW babies was 26 weeks’ gestational age. 85% of the ELBW babies with a gestational age of less than 26 weeks died; on the contrary, 86.4% of the neonates born more than 26 weeks gestation survived. In Group 1, the babies born from singleton pregnancy were prevalent (61.4%); in Group 2, there were no signif icant differences in the number of fetuses. Among the multiple births in Group 1, the proportion of bichorial and monochorial twins was approximately equal and, in Group 2, the monochorial twins were predominant (72.7%). Group 1 had high cesarean section rates (95.5%); in Group 2, only 45% of the women delivered abdominally. Conclusion. The best survival was observed in ELBW infants born at 26 weeks gestation or; moreover, abdominal delivery was preferred. At less than 26 weeks gestation, the mode of delivery and fetal presentation did not increase the likelihood of a favorable outcome.

Full Text

Restricted Access

About the authors

N. V BASHMAKOVA

Research Institute of Maternal and Infancy Care, Ministry of Health of the Russian Federation

Email: zamdirnir@k66.ru
Yekaterinburg

A. V KAYUMOVA

Research Institute of Maternal and Infancy Care, Ministry of Health of the Russian Federation

Email: kaum-doc@mail.ru
Yekaterinburg

O. A MELKOZEROVA

Research Institute of Maternal and Infancy Care, Ministry of Health of the Russian Federation

Email: abolmed1@mail.ru
Yekaterinburg

References

  1. Радзинский В.Е., Оразмурадов А.А., ред. Ранние сроки беременности. 2-е изд. M.: Status Praesens; 2009. 480 с.
  2. Сидельникова В.М. Невынашивание беременности -современный взгляд на проблему. Российский вестник акушера-гинеколога. 2007; 2: 62-4.
  3. Choi Y.K., Kwak-Kim J. Cytokine gene polymorphisms in recurrent spontaneous abortions: a comprehensive review. Am. J. Reprod. Immunol. 2008; 60(2): 91-110.
  4. Christiansen O.B., Steffensen R., Nielsen H.S., Varming K. Multifactorial etiology of recurrent miscarriage and its scientific and clinical implications. Gynecol. Obstet. Invest. 2008; 66(4): 257-67.
  5. Yang C.J., Stone P., Stewart A.W. The epidemiology of recurrent miscarriage: a descriptive study of 1214 prepregnant women with recurrent miscarriage. Aust. N. Z. J. Obstet. Gynaecol. 2006; 46(4): 316-22.
  6. Czernobilsky B. Endometritis and infertility. Fertil. Steril. 1978; 30(2): 119-30.
  7. Aoki K., Kajiura S., Matsumoto Y., Ogasawara M., Okada S., Yagami Y., Gleicher N. Preconceptional natural killer cell activity as a predictor of miscarriage. Lancet. 1995; 345(8961): 1340-2.
  8. Klentzeris L.D. The role of endometrium in implantation. Hum. Reprod. 1997; 12(11, Suppl): 170-5.
  9. Li T.C., Tuckerman E.M., Laird S.M. Endometrial factor in recurrent miscarriage. Hum. Reprod. Update. 2002; 8(1): 43-52.
  10. Sebire N.J. Choriodecidual inflammatory syndrome (CoDIS) is the leading and under recognized, cause of early preterm delivery and second trimester miscarriage. Med. Hypotheses. 2001; 56(4): 497-500.
  11. Subramanian S., Rosenkrantz T.B. Extremely low birth weight infant. Medscape Referens. 2012; October 2: 2-3.
  12. Martin J.A., Kung H.C., Mathews T.J., Hoyert D.L., Strobino D.M., Guyer B., Sutton S.R. Annual summary of vital statistics: 2006. Pediatrics. 2008; 121(4): 788-801.
  13. Lasswell S.M., Barfield W.D., Rochat R.W., Blackmon L. Perinatal regionalization for very low-birth-weight and very preterm infants: a meta-analysis. JAMA. 2010; 304(9): 992-1000.
  14. Lemons J.A., Bauer C.R., Oh W., Korones S.B., Papile L.A., Stoll B.J. et al. Very low birth weight outcomes of the National Institute of Child Health and human development neonatal research network, January 1995 through December 1996. NICHD Neonatal Research Network. Pediatrics. 2001; 107(1): E1.
  15. Groen-Blokhuis M.M., Middeldorp C.M., van Beijsterveldt C.E., Boomsma D.I. Evidence for a causal association of low birth weight and attention problems. J. Am. Acad. Child Adolesc. Psychiatry. 2011; 50(12): 1247-54; e2.

Supplementary files

Supplementary Files
Action
1. JATS XML

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies