BIOLOGICAL ROLE OF VAGINAL ACIDITY. STABILITY MECHANISMS AND CORRECTION METHODS
- Authors: KIRA E.F1, DUSHKINA E.A1, BADIKOVA N.S1
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Affiliations:
- N.I. Pirogov National Medical and Surgical Center, Ministry of Health of Russia
- Issue: No 3 (2013)
- Pages: 102-106
- Section: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/246994
- ID: 246994
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Abstract
The role of lactic acid in maintaining the homeostasis of a vaginal biotope is of great importance. Vaginal acidity is maintained under natural conditions through the functional activity of vaginal epitheliocytes and lactobacilli. If the environmental pH is unstable, vaginal acidity may be corrected with local lactic acid preparations; in this connection there can be no question that investigations of the efficacy of novel current acid-containing drugs, their dosage, and treatment regimens for bacterial vaginosis are urgent and promising. The first Russian designed lactic acid-containing vaginal suppositories 100 mg (femilex) are becoming an alternative to conventional antibacterial therapy for bacterial vaginosis. It is possible that lactic acid therapy in the decreased, but preserved lactoflora will be able to rule out the second stage of using of probiotics.
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About the authors
E. F KIRA
N.I. Pirogov National Medical and Surgical Center, Ministry of Health of Russia
Email: profkira33@gmail.com
E. A DUSHKINA
N.I. Pirogov National Medical and Surgical Center, Ministry of Health of Russia
Email: e-dushkina@mail.ru
N. S BADIKOVA
N.I. Pirogov National Medical and Surgical Center, Ministry of Health of Russia
Email: Natalya-badikova@yandex.ru
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