Vaginal discharge in gynecological patients: Etiology and approaches to diagnosis


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Abstract

Objective. To estimate the informative value of clinical and laboratory data in examining patients complaining of vaginal discharge. Subjects and methods. The investigation enrolled 200 non-pregnant women who had sought gynecological advice for complaints of vaginal discharge. Examinations of all the patients and collection of their history data allowed the investigators to obtain materials for further laboratory studies using microscopy and real-time polymerase chain reaction (RT-PCR). Results. The examinees were found to have sexually transmitted infections in 18 (9.55) cases, bacterial vaginosis in 52 (27.5%), vulvovaginal candidiasis in 58 (30.7%), and aerobic vaginitis in 7(3.7%). The diagnostic sensitivity and specificity of clinical findings and microscopy proved to be low for all nosological entities. Conclusion. The most rational approach to examining patients with vaginal discharge was microscopy for evaluation of mucosal inflammation and RT-PCR for detection of the causative agents of respiratory infections.

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About the authors

T. A Rumyantseva

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Welfare

Email: Ivanovatatiana86@yandex.ru
Researcher, Gynecologist, Laboratory of Molecular Diagnostics and Epidemiology of infections of reproductive organs, Clinical Diagnostic Center

V. A Sursyakov

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Welfare

Email: sursyakov@gmail.com
PhD, Gynecologist, Clinical Diagnostic Center, Central Research Institute of Epidemiology

G. A Khairullina

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Welfare

Email: guzel.khairullina@gmail.com
PhD, Researcher, Laboratory of Molecular Diagnostics and Epidemiology of infections of reproductive organs, Central Research Institute of Epidemiology

L. A Chernyshova

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Welfare

Email: lora.chernyshova@gmail.com
Junior Researcher, Laboratory of Molecular Diagnostics and Epidemiology of infections of reproductive organs

A. E Gushchin

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Welfare

Email: aguschin1965@pcr.ru
PhD, Head of the Laboratory of Molecular Diagnostics and Epidemiology of infections of reproductive organs

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