Analysis of approaches to treating seasonal allergic rhinitis in pregnant women


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Abstract

Approximately 20-30% of reproductive-aged women suffer from seasonal allergic rhinitis, the uncontrolled course of which during pregnancy can not only worsen the quality of life and the course of comorbidities, but also give rise to maternal and fetal hypoxia. Objective. To analyze approaches to treating seasonal allergic rhinitis in pregnant women. Subjects and methods. An anonymous questionnaire survey of physicians (332 therapists and 734 obstetricians/ gynecologists) was conducted within the study “Epidemiology of Medication Use in Pregnant Women” (Stage 2); the clinical guidelines of foreign and Russian professional societies for this problem were analyzed. Results. The physicians rarely indicated topical steroids (8.4%); first-generation antihistamines were the leaders (29.7%); the physicians less often indicated second-generation drugs, such as loratadine (13.8%) and cetirizine (10.7%). Conclusion. In accordance with the guidelines, the approach to treating allergic rhinitis in pregnant women should be the same as applied to other patients; an important part is assigned to nondrug therapies. By taking into account the high prevalence of this disease, it is appropriate to do educational work on this problem among physicians.

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About the authors

Anastasia A. Kameleva

Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health Russia

Email: extralab@mail.ru
PhD, Senior Researcher of the Therapeutic Department

Natalia A. Chukhareva

Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health Russia

Email: 0330348@gmail.com
Junior Researcher of the Therapeutic Department

Evgeniya O. Khalturina

Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health Russia

Email: extralab@mail.ru
PhD, Researcher of the Therapeutic Department

Roza M. Esayan

Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health Russia

Email: rozaes@mail.ru
PhD, head of the Therapeutic Department

Elena A. Ushkalova

Peoples’ Friendship University of Russia

Email: eushk@yandex.ru
MD, Professor of the department of Basic and Clinical Pharmacology

Olga N. Tkacheva

Stand-alone structural unit of RNRMU The Russian Clinical Research Center for Gerontology

Email: ontkacheva@gmail.com
MD, Professor, Director

Alina Yu. Bevz

Stand-alone structural unit of RNRMU The Russian Clinical Research Center for Gerontology

Email: alinka16@list.ru
PhD, Researcher

Ekaterina V. Eliseeva

Pacific State Medical University

Email: yeliseeff@rbcmaM.ru
MD, Professor, Head of Basic and Clinical Pharmacology Chair

Nikolay G. Filippenko

Kursk State Medical University

Email: clinfarm@kursknet.ru
MD, Professor of the department of Clinical Pharmacology

Galina V. Chizhova

Postgraduate Institute for Public Health Workers

Email: rec@ipksz.khv.ru
MD, Professor, Rector

A. I Malyshkina

Email: niimid@ivnet.ru

Roman A. Bontsevich

Belgorod State National Research University

Email: bonts@mail.ru
MD, PhD, assistant professor, Pharmacology department

Nadezhda G. Vinogradova

Nizhny Novgorod State Medical Academy

Email: vinogradovang@yandex.ru
PhD, Assistant, Department of internal diseases

Vasiliy S. Chulkov

South Ural State Medical University

Email: vschulkov@rambler.ru
PhD, associate professor

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