Email this article The redox properties and antiradical activity of terpenophenols
- Authors: Polovinkina M.A.1, Kolyada M.N.2, Osipova V.P.2, Berberova N.T.1, Chukicheva I.Y.3, Shumova O.A.3, Kutchin A.V.3
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Affiliations:
- Astrakhan State Technical University
- Federal State Budget Institution of Science "Federal Research Center The Southern Scientific Centre of the Russian Academy of Sciences"
- Komi Science Centre of the Ural Branch of the Russian Academy of Sciences
- Issue: Vol 484, No 5 (2019)
- Pages: 568-571
- Section: Chemistry
- URL: https://journals.eco-vector.com/0869-5652/article/view/12774
- DOI: https://doi.org/10.31857/S0869-56524845568-571
- ID: 12774
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Abstract
The redox properties and antiradical activity of terpenophenols (2,6-diisobornyl-4-methylphenol and 3-isocamphyl-2-naphthol) in comparison with BHT (butylhydroxytoluol, 2,6-di-tret-butyl-4-methylphenol) have been studied. The terpenophenols have been shown to react more readily in electron transfer processes as compared with BHT, and they have been found to react with electrochemically generated superoxide radical anion (О2•–). The effect of the compounds on the rate of generation upon adrenaline oxidation in an alkaline medium and the ability of biopreparations based on Russian sturgeon liver and gonad homogenates to deactivate have been studied. Adrenaline oxidation inhibition and the increase in superoxide dismutation activity of the biopreparations in the presence of terpenophenols have been shown, and this fact can indicate the ability of these compounds to decrease the probability of oxidative stress enlargement. A correlation has been established between the redox properties and antioxidant activity of terpenophenols in the model system of adrenaline oxidation in the presence of the biopreparations.
About the authors
M. A. Polovinkina
Astrakhan State Technical University
Author for correspondence.
Email: osipova_vp@mail.ru
Russian Federation, 16, Tatischeva street, Astrakhan, 414056
M. N. Kolyada
Federal State Budget Institution of Science "Federal Research Center The Southern Scientific Centre of the Russian Academy of Sciences"
Email: osipova_vp@mail.ru
Russian Federation, 41, Chekhova street, Rostov-on-Don, 344006
V. P. Osipova
Federal State Budget Institution of Science "Federal Research Center The Southern Scientific Centre of the Russian Academy of Sciences"
Email: osipova_vp@mail.ru
Russian Federation, 41, Chekhova street, Rostov-on-Don, 344006
N. T. Berberova
Astrakhan State Technical University
Email: osipova_vp@mail.ru
Russian Federation, 16, Tatischeva street, Astrakhan, 414056
I. Yu. Chukicheva
Komi Science Centre of the Ural Branch of the Russian Academy of Sciences
Email: osipova_vp@mail.ru
Russian Federation, 24, Kommunisticheskaya street, Syktyvkar, 167982
O. A. Shumova
Komi Science Centre of the Ural Branch of the Russian Academy of Sciences
Email: osipova_vp@mail.ru
Russian Federation, 24, Kommunisticheskaya street, Syktyvkar, 167982
A. V. Kutchin
Komi Science Centre of the Ural Branch of the Russian Academy of Sciences
Email: osipova_vp@mail.ru
Corresponding Member of the RAS
Russian Federation, 24, Kommunisticheskaya street, Syktyvkar, 167982References
- Бурлакова Е.Б., Алесенко А.В., Молочкина Е.М., Пальмина Н.П., Храпова Н.Г. Биоантиоксиданты в лучевом поражении и злокачественном росте. М.: Наука, 1975. 214 с.
- Li X.L., Zhou A.G. // Chem. Res. 2007. V. 15. Р. 471–482.
- Чукичева И.Ю., Шумова О.А., Супоницкий К.Ю., Кучин А.В. // Изв. РАН. Сер. хим. 2011. № 3. С. 496–500.
- Мазалецкая Л.И., Шелудченко Н.И., Шишкина Л.Н., Кучин А.В., Чукичева И.Ю. // Нефтехимия. 2011. Т. 28. № 1. С. 78–80.
- Плотников М.Б., Смольякова В.И., Иванов И. С., Кучин А.В., Чукичева И.Ю., Краснов Е.А. // Бюл. эксперим. биологии и медицины. 2008. Т. 145. № 3. С. 296–299.
- Плотников М.Б., Чернышева Г.А., Смольякова В.И., Иванов И.С., Кучин А.В., Чукичева И.Ю., Краснов Е.А. // Вестн. РАМН. 2009. Т. 11. С. 12–17.
- Chukicheva I.Yu., Fedorova I.V., Buravlev E.V., Lumpov A.E., Vikharev Yu.B., Anikina L.V., Grishko V.V., Kutchin A.V. // Chem. Nat. Compounds. 2010. V. 46. № 4. Р. 478–480.
- Chevion S., Roberts M.A., Chevion M. // Free Radic. Biol. Med. 2000. V. 28. P. 860–870.
- Тюрин В.Ю., Изинвей Чжан, Моисеева А. А., Милаева Е.Р., Белых Д.В., Буравлев Е.В., Рочева Т.К., Чукичева И.Ю., Кучин А.В. // ДАН. 2013. Т. 450. № 5. С. 543–546.
- Peyrat-Maillard M.N., Bonnely S., Berset C. // Talanta. 2000. V. 51. P. 709–716.
- Зиятдинова Г.К., Захарова С.П., Будников Г.К. // Уч. зап. Казан. ун-та. 2015. Т. 157. Кн. 2. C. 129–142.
- Magalhres L.M., Segundo M.A., Reis S., Lima J. L.F.C. // Anal. Chim. Acta. 2008. V. 613. № 1. Р. 1–19.
- Сирота Т.В. // Вопр. мед. химии. 1999. Т. 45. № 3. С. 263–272.
- Sheng Y., Abreu I.A., Cabelli D.E., Maroney M.J., Miller Anne-Frances, Teixeira M., Valentine J.S. // Chem. Rev. 2014. V. 114. P. 3854–3918.
- Shiva M., Gautam A.K, Verma Y., Shivgotra V., Doshi H., Kumar S. // Clin. Biochem. 2011. V. 44. P. 319–324.
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