Hydrogels and sponge materials based on triblock copolymers of lactide and ethylene glycol

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Abstract


New techniques have been developed for the preparation of spongy materials and hydrogels based on triblock copolymers of lactide and ethylene glycol with various molecular structures. The influence of the composition of the initial copolymers and supramolecular structure on their mechanical characteristics and biocompatibility was studied. Cytological studies have shown that all materials have a high level of cell viability (GSP). The possibility of obtaining hydrogels with elastic moduli up to 4460 kPa, a record for such systems, was shown.


About the authors

Y. D. Zagoskin

National Research Centre "Kurchatov Institute"

Author for correspondence.
Email: zagos@inbox.ru

Russian Federation, 1, Kurchatov square, Moskow, 123182

T. E. Grigoriev

National Research Centre "Kurchatov Institute"

Email: zagos@inbox.ru

Russian Federation, 1, Kurchatov square, Moskow, 123182

S. V. Krasheninnikov

National Research Centre "Kurchatov Institute"

Email: zagos@inbox.ru

Russian Federation, 1, Kurchatov square, Moskow, 123182

E. V. Cuevda

Kuban State Medical University of the Ministry of Healthcare of the Russian Federation

Email: zagos@inbox.ru

Russian Federation, 4, Mitrofana Sedina Street, Krasnodar, Russian Federation, 350063

E. A. Gubareva

Kuban State Medical University of the Ministry of Healthcare of the Russian Federation

Email: zagos@inbox.ru

Russian Federation, 4, Mitrofana Sedina Street, Krasnodar, Russian Federation, 350063

A. V. Bakirov

National Research Centre "Kurchatov Institute"; Institute of synthetic polymeric materials of the Russian Academy of Sciences

Email: zagos@inbox.ru

Russian Federation, 1, Kurchatov square, Moskow, 123182; 70, Profsoyuznaya street, Moscow, 117393

S. N. Chvalun

National Research Centre "Kurchatov Institute"; Institute of synthetic polymeric materials of the Russian Academy of Sciences

Email: zagos@inbox.ru
1, Kurchatov square, Moskow, 123182; 70, Profsoyuznaya street, Moscow, 117393

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