Artificial intelligence-based information technologies in the era of personalized health assessment

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Abstract

Introduction. Personalized (precision) medicine is rapidly changing modern healthcare, shifting the focus from disease treatment to prevention and individualized patient approach. The integration of artificial intelligence (AI) technologies and molecular medicine opens new opportunities for early disease detection, risk factor (RF) assessment, and selection of optimal prevention and therapy considering genetic characteristics.

Objective. To analyze the role of AI-based information technologies in the context of personalized (molecular) medicine.

Material and methods. Scientific publications from the last 5 years were analyzed from PubMed and Scopus databases, demonstrating the effectiveness of AI algorithms in early diagnostics, successful examples of whole genome sequencing application, polygenic risk indices, and other genetic technologies for disease prediction.

Results. Modern AI-based information technologies in the context of personalized health assessment are considered: screening programs, intelligent analysis of medical data, genomic and other «omics» technologies. The prospects for implementing AI in clinical practice are discussed, including multimodal models combining clinical and molecular data, and current barriers (lack of resources, regulatory restrictions, ethical issues) to the implementation of personalized medicine are considered.

Conclusion. Digital molecular medicine using AI improves the effectiveness of disease prevention, diagnosis, and treatment, which is confirmed by both clinical and economic indicators, but requires a comprehensive approach to implementation and standardization.

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About the authors

Pavel V. Seliverstov

Federal State Budgetary Military Educational Institution of Higher Education “Military Medical Academy named after S.M.Kirov” of the Ministry of Defense of the Russian Federation

Author for correspondence.
Email: seliverstovpv@yandex.ru
ORCID iD: 0000-0001-5623-4226
SPIN-code: 6166-7005

Associate Professor of the 2nd Department (advanced medical therapy), Candidate of Medical Sciences, Associate Professor

Russian Federation, Lebedeva St., 6, Saint Petersburg, 194044

Valentin V. Shapovalov

Peter the Great St. Petersburg Polytechnic University

Email: valshapovalov@mail.ru
ORCID iD: 0000-0002-9764-4018
SPIN-code: 7996-2771

Professor of the Institute of Biomedical Systems and Biotechnology, Doctor of Technical Sciences, Professor

Russian Federation, Politechnicheskaya str., 29, St. Petersburg, 194064

Yurii A. Kravchuk

Federal State Budgetary Military Educational Institution of Higher Education “Military Medical Academy named after S.M.Kirov” of the Ministry of Defense of the Russian Federation

Email: kravchuk2003@mail.ru
ORCID iD: 0000-0001-8347-0531
SPIN-code: 6767-5189

Professor of the 2nd Department (Therapy for Advanced Medical Studies), Doctor of Medical Sciences, Professor

Russian Federation, Lebedeva St., 6, Saint Petersburg, 194044

Svetlana P. Salikova

Federal State Budgetary Military Educational Institution of Higher Education “Military Medical Academy named after S.M.Kirov” of the Ministry of Defense of the Russian Federation

Email: salikova.1966@bk.ru
ORCID iD: 0000-0003-4839-9578
SPIN-code: 2012-8481

Professor of the 2nd Department (Therapy for Advanced Medical Studies), Doctor of Medical Sciences, Professor

Russian Federation, Lebedeva St., 6, Saint Petersburg, 194044

Fatima V. Shavaeva

Kabardino-Balkarian State University named after H.M. Berbekov

Email: shavaevafv@mail.ru
ORCID iD: 0000-0002-1767-9975

Associate Professor of the Medical Academy, Candidate of Biological Sciences

Russian Federation, Chernyshevsky St., 173, Nalchik, 360004

Patimat A. Isaeva

Federal State Budgetary Educational Institution of Higher Education “Dagestan State Medical University”, Ministry of Health of the Russian Federation

Email: isaeva_80@inbox.ru
ORCID iD: 0009-0005-5140-320X

Postgraduate Student

Russian Federation, Lenin Square, 1, Makhachkala, 367000

Madina M. Salmanova

Federal State Budgetary Educational Institution of Higher Education “Dagestan State Medical University”, Ministry of Health of the Russian Federation

Email: 1258madina1258@gmail.com
ORCID iD: 0009-0006-0149-6644

6th year Student

Russian Federation, Lenin Square, 1, Makhachkala, 367000

Rukiyat M. Arslanbekova

Federal State Budgetary Educational Institution of Higher Education “Dagestan State Medical University”, Ministry of Health of the Russian Federation

Email: dggfddvhfdghv@gmail.com
ORCID iD: 0009-0000-6076-0106

6th year student

Russian Federation, Lenin Square, 1, Makhachkala, 367000

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