Approaches to more effective radical prostatectomy


Cite item

Full Text

Abstract

In search of ways to improve the results of radical surgical treatment of patients with prostatic cancer (PC), we analysed the results of examination and treatment of 130 patients with local PC performed in 2000-2010 years. All the patients have undergone retropubic radical prostatectomy (RPE). Of them, 25.4% received neoadjuvant hormonal therapy. Follow-up median was 53 months (16-122 months). We also estimated direct and indirect costs of RPE. Erectile dysfunction after RPE was registered in 93.1% patients, urinary incontinence - in 20% patients, anastomosis stricture - in 22.6%. Five and 10 year recurrence-free survival was 80 and 72%, respectively. Total (direct and indirect) costs of one PC patient's surgical treatment (RPE) reached 140891,29 roubles. Our calculations show that certain measures taken in practical activity of the urologists can reduce direct costs by about 25%. Thus, our study demonstrates that it is possible to avoid unjustified expenses and achieve good outcomes in surgical treatment of PC.

References

  1. Распоряжение Правительства Российской Федерации от 17 нояб. 2008 г. № 1662-р "О Концепции долгосрочного социально-экономического развития Российской Федерации на период до 2020 года". Доступ из справочно-правовой системы "Консультант Плюс".
  2. Чиссов В. И., Старинский В. В., Петров Г. В. (ред.). Злокачественные новообразования в России в 2008 году (заболеваемость и смертность). М.: ФГУ "МНИОИ им. П. А. Герцена Росмедтехнологий", 2010.
  3. Чиссов В. И., Старинский В. В., Петров Г. В. (ред.).Состояние онкологической помощи населению России в 2008 году. М.: ФГУ "МНИОИ им. П. А. Герцена Росмедтехнологий"; 2010.
  4. http://www.gks.ru
  5. http://www.sf.ru
  6. Постановление Правительства Российской Федерации от 2 окт. 2009 г. № 811 "О Программе государственных гарантий оказания гражданам Российской Федерации бесплатной медицинской помощи на 2010 год". Доступ из справочно-правовой системы "Консультант Плюс".
  7. http://www.uro.ru
  8. http://www.legmed.ru
  9. http://www.inter-orm.narod.ru/lomrauch.htm
  10. http://www.mednitki.ru/shop/ index.php?Kategory = Полисорб
  11. http://www.infomedopt.ru
  12. Ficarra V., Novara G., Artibani W. et al. Retropubic, laparoscopic, and robot-assisted radical prostatectomy: a systematic review and cumulative analysis of comparative studies. Eur. Urol. 2009; 55 (5): 1037-1063.
  13. Bianco Jr. F. J., Scardino P. Т., Eastham J. A. Radical prostatectomy: long-term cancer control and recovery of sexual and urinary function ("trifecta"). Urology 2005; 66 (Suppl. 5): 83- 94.
  14. Saranchuk J. W., Kattan M. W., Elkin E. et al. Achieving optimal outcomes after radical prostatectomy. J. Clin Oncol. 2005; 23 (18): 4146-4151.
  15. Han M., Partin A. W., Pound C. R. et al. Long-term biochemical disease-free and cancer-specific survival following anatomic radical retropubic prostatectomy. The 15-year Johns Hopkins experience. Urol. Clin. N. Am. 2001; 28(3): 555-565.
  16. Roehl K. A., Han M., Ramos C. G. et al. Cancer progression and survival rates following anatomical radical retropubic prostatectomy in 3478 consecutive patients: long-term results. J. Urol. (Baltimore) 2004; 172(3): 910-914.
  17. Chun F. K., Graefen M., Zacharias M. et al. Anatomic radical retropubic prostatectomy: long-term recurrence-free survival rates for localized prostate cancer. Wld J. Urol. 2006; 24(3): 273-280.
  18. Link R. E., Su L. M., Bhayani S. B., Pavlovich C. P. Making ends meet: a cost comparison of laparoscopic and open radical retropubic prostatectomy. J. Urol. (Baltimore) 2004; 172(1): 269-274.
  19. Lotan Y., Cadeddu J. A., Gettman M. T. The new economics of radical prostatectomy: cost comparison of open, laparoscopic and robot assisted techniques. J. Urol. (Baltimore) 2004; 172(4, Pt 1) 1431-1435.
  20. Anderson J. K., Murdock A., Cadeddu J. A., Lotan Y. Cost comparison of laparoscopic versus radical retropubic prostatectomy. Urology 2005; 66(3) 557-560.
  21. O'Malley S. P., Jordan E. Review of a decision by the Medical Services Advisory Committee based on health technology assessment of an emerging technology: the case for remotely assisted radical prostatectomy. Int. J. Technol. Assess. Hlth Care 2007; 23(2): 286-291.
  22. Bolenz C., Gupta A., Hotze T. et al. Cost comparison of robotic, laparoscopic, and open radical prostatectomy for prostate cancer. Eur. Urol. 2010; 57(3): 453-458.
  23. http://www.uroweb.org/gls/pdf/Prostate%20Cancer%202010%20June%2017th pdf
  24. Lepor H., Nieder A. M., Ferrandino M. N. Intraoperative and postoperative complications of radical retropubic prostatectomy in a consecutive series of 1000 cases. J. Urol. (Baltimore) 2001; 166(5): 1729-1733.
  25. Augustin H., Hammerer P., Graefen M. et al. Intraoperative and perioperative morbidity of contemporary radical retropubic prostatectomy in a consecutive series of 1243 patients: results of a single center between 1999 and 2002. Eur. Urol. 2003; 43(2): 113-118.
  26. Lepor H. Open versus laparoscopic radical prostatectomy. Rev. Urol. 2005; 7(3): 115-127.
  27. Paulson D. F. Impact of radical prostatectomy in the management of clinically localized disease. J. Urol. (Baltimore) 1994; 152(5, Pt 2) : 1826-1830.

Supplementary files

Supplementary Files
Action
1. JATS XML

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies