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No 2 (2016)



Komyakov B.K.


Aim. To examine the results of intestinal ureteroplasty and present the technical features of left-sided ileoureteroplasty. Material and methods. From 2001 to 2015, 78 patients underwent isolated substitutions of the ureter using a segment of the ileum, including 57 (73.1%) one-sided and 21 (26.9%), two-sided. One patient underwent concurrent left ileoureterocystoplasty and right appendicular ureterocystoplasty. In two observations of duplicated ureter Wallace-type ileoureterocystoplasty was carried out. In total, isolated segments of the ileum were used to substitute 101 ureters. Left and right ureters were substituted in 56 (55.4%) and 45 (44.6%) patients, respectively. In 7 (8.9%) patients laparoscopic approach was used. Results. Early postoperative complications occurred in 8 (10.2%) patients and 5 (6.4%) of them required reoperation. Long-term postoperative complications occurred in 7 (8.9%) patients and 4 required surgical treatment. These patients developed strictures of ileal-ureteral anastomosis 3 and more months after surgery. Urinary tract patency was restored by antegrade stricture dilation. All patients were found to have good results of conservative treatment and repeated operations. There were no deaths. All patients achieved restoration of urodynamics and normalization of kidney function. Conclusion. Using isolated segment of the ileum allows replacing the defects of one or both ureters of any location and extent. Left-sided ileoureteroplasty is one of the most developed and simple modifications of gastrointestinal ureteral reconstructions. Isoperistaltic substitution of the left ureter is possible when the ileo-transplant is below and behind the intestinal anastomosis. The graft should be placed in isoperistaltic position and intraperitoneally, i.e. be left it in the conditions inherent in this organ.
Urologiia. 2016;(2):4-9
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Konoplya A.I., Bratchikov O.I., Kholimenko I.M., Shatokhin M.N., Dzharimok A.R., Mavrin M.Y., Loktionov A.L.


Aim. Studying of a condition of the immune status on for standard treatment at an acute serous and purulent pyelonephritis. Materials and methods. The immune status of 62 patients with various forms of an acute pyelonephritis, randomized on age, sex, the minimum quantity of associated diseases in a remission stage is surveyed. Results and their discussion. Purulent form of acute pyelonephritis was accompanied by higher levels of pro-inflammatory cytokines with decreased levels of anti-inflammatory cytokines. In serous form, imbalance in the cytokine system was found. Both serous and purulent forms of pyelonephritis were characterized by the imbalance in the complement system, increased production of immunoglobulins with simultaneous reduction of circulating immune complexes, decreased activity and the intensity of phagocytosis with increased metabolic activity of neutrophils. Conclusion. At serous and purulent forms of a pyelonephritis there are differences in an orientation and expression of changes of the immune indicators demanding development of methods of the differentiated immunorehabilitation.
Urologiia. 2016;(2):10-17
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Imamverdiyev S.B., Talybov T.A.


Aim. Improvement in the results of the treatment of patients suffering from staghorn and multiple nephrolithiasis, using open method of surgery and a retrospective analysis of the surgical data. Material and methods. There was executed asurgical treatment of the 730 patients with staghorn and multiple nephrolithiasis in the period from 1998 to 2012. 480 of the patients had one-sided staghorn stones and 250 of them had double-sided staghorn stones. Age of the patients varied from 4 to 76 years old (average - 49). There were 351 men (48,0%) and 379 women (51,9 %). 290 (39,8%) patients had only staghorn stones, but 440 (60,2%) patients suffered from staghorn stones combining with multiple ones. Results. There were executed 1065 surgical operations at the 730 patients. There was used pyelotomy and nephrolithotomyfor the purpose of the ablation of stones. Nephrostomy was placed on the right of the 116patients (15,8%), on the left - 93patients (12,7%), pyelostomy on the right - 46 patients (6,3%), on the left - 31patients (4,2%), intrarenalstent on the right - 181 patients (24,7%), on the left - 167patients (22,8%), stent and nephrostomy on the right - 29 patients (3,9%), on the left - 6 patients (0,8%). Surgical operations of 184 patients (25,2%)fulfilled throughcross-clamping of the nephritic artery.Cross-clamping time of the nephritic artery in average was 16.5 minutes (5-50), average duration of the surgical operation - 2,6 hours (1,5-6), intraoperative hemorrhage - 110 ml (50-300). During the re-examination there was found that 175 patients (23,9%) had recurrent stones.During first ten years after operation there were found recurrent stones at 238 patients (32,6%), 100 (13,6%) of them had the second operation. Conclusion. Taking into account that minimally invasive methods of the staghorn and multiple nephrolithiasistreatment is ineffective and demand a few courses of medical treatment, open surgical operations still have a leading positions as they create extensive possibilities for the favorable and safe revision of the kidney during ablation of stones.
Urologiia. 2016;(2):18-22
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Al'-Shukri S.K., Slesarevskaya M.N., Kuz'min I.V.


Aim. To evaluate the effectiveness of ESWL combined with litholytic therapy in patients with uric acid kidney stones. Materials and methods. A total of 59 patients with urate nephrolithiasis were observed at the Department of Urology, First Pavlov SMU of St. Peterburg. The patients were divided into two groups according to the treatment regimen. The study group comprised 30 patients who were administered litholytic therapy before ESWL. The comparison group included 29 patients with nephrolithiasis who underwent ESWL without prior litholytic therapy. Results. After 4 weeks of treatment with Blemaren, in 60% of patients of the study group a decrease in the calculus size was noted; in 83.3% of patients according to MSCT there was a decrease in calculus density. Disintegration of kidney stones after a single ESWL session was achieved in 86.7% of patients of the study group and in 65.5% of patients of the control group. Conclusion. The results of this study allow us to recommend a 4-week course of Blemaren to treat patients with urate nephrolithiasis to prepare for ESWL.
Urologiia. 2016;(2):23-27
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Tatevosyan A.S., Tonyan A.G., Medvedev V.L., Gdamarova O.I.


Aim. To develop a method for early diagnosis of renal venous blood flow disorders as a factor determining complicated course of hypermobile kidney (HK). Material and methods. Rotation angles in the three coordinate planes and six static conditions were determined in 92 patients with HK (in 3312 coordinate planes and in 1104 the static state). The fixed probe and "dancing kidney” method was used. The same 92 patients underwent polypositional Doppler sonography in six static states. Statistical analysis was performed using the statistical software STATISTICA 7.0 (Statsoft Inc., USA). Results. In 226 (93%) patients with HK ASAD exceeded 30 mm Hg in at least one static state. Evaluation of 552 variants in assessing hemodynamic features of hypermobile kidney revealed that 92 patients had signs of impaired unilateral or bilateral renal vein outflow as determined by RMS and dVven. in 415 (75.18%) cases. The accuracy in determining belonging to the group, according to the classification matrices of STATISTICA 7.0 software was 89.13%. Discussion. The developed methods for evaluating kidney rotation make it possible to diagnose significant disturbances of the renal major blood flow and monitor dynamics of the process in real-time. All disturbances of the renal major blood flow occur only in ptosis and rotation; that confirms the need for early diagnosis of these conditions. Conclusion. The findings of the multi-positional study of HK and the results of the data mathematical processing suggest that our method of HK imaging enables screening to determine the group of patients in need of further examination and observation.
Urologiia. 2016;(2):28-32
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Sergevnin V.I., Klyuchareva N.M., Antipin D.P., Laricheva E.N.


The goal of the research is to compare and evaluate the efficiency of using silver - coated silicone urinary catheters and catheters without coating for prevention urinary tract infections. Materials and methods. The study included 57 adult patients of intensive care unit, which have silicone bladder catheters «Foley» without coating, and 57 patients were catheterized using catheters coated with silver. We revealed symptomatic and asymptomatic urinary tract infections in our research. Results. During the 14-day bladder catheterization period the preventive effect of urethral silicone catheters coated with silver for prevention of manifest and subclinical urinary tract infections was determined.
Urologiia. 2016;(2):33-36
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Gaibullaev A.A., Iskandarova G.T., Abdurizaev A.A.


Objective: To estimate prevalence and types of urinary incontinence (UI) among women living in the South Priaralye region, and to analyze risk factors associated with UI. Materials and methods. The population-based study was conducted by nested-typological method. Analysis was carried out on the data of 1487 women collected by a standard ICIQ-SF questionnaire, an assessment tool for female urinary incontinence recommended by the European Association of Urology. Results. The study showed that the prevalence of UI among women aged 18 years and older in the South Priaralye region was 27%. The predominant type of the disease was stress UI since in 44.8% of women, the uncontrolled urine loss occurred during exercise. In 16.1% of women urgent type UI was observed, and in 38.6% mixed type of UI was found. The most significant risk factors for UI were recurrent urinary tract infection (odds ratio (OR) of 5.9 (95% confidence interval (CI) 4.12-8.38), gynecological disease (OR 2.7 (95% CI 1.99-3.59), enuresis in childhood (OR 2.4 (95% CI 1.21-4.88), constipation (OR = 2.1 (95% CI 1.45-2.93) the number of births (OR = 1.2 (95% CI 1,05-1.28), and occupation, namely work involving physical strain (odds ratio of 1.2 (95% CI 1.04-1.43). Conclusion. In the area of the South Priaralye, more than a fourth of adult females were found to have a UI. Understanding the nature and risk factors for UI will allow planning the resources required to provide treatment and preventive measures in the future.
Urologiia. 2016;(2):37-42
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Apolikhin O.I., Sivkov A.V., Yanenko E.K., Katibov M.I., Zolotukhin O.V., Shaderkin I.A., Prosyannikov M.Y., Voitko D.A., Tsoi A.A., Galiev N.A., Kastrikin Y.V.


Aim. To evaluate the incidence of acute urinary retention as an indicator of the quality of care for patients with benign prostatic hyperplasia by the example of "Urology" Program implemented in the Voronezh region. Materials and methods. As part of the program "Urology", the incidence of AUR was used as an indicator of quality of care for patients with BPH. Urological health care for patients with BPH was provided within a three-stage model. For each of the stages standardized packages of detailed methodological materials, including regional standards were developed. Results. Over the 3 years of the program (2011-2013) questionnaire survey was conducted among 762 937 men 50-75 years old with 85.3-88.1% annual coverage of respondents. Over the past three years (2009-2012) there was consistent and statistically significant (p<0.05) decrease (from 11.27 to 1.5%) in the proportion of hospitalizations for AUR reaching a “plateau” (p>0.05) in 2012-2013. There was a significant correlation of AU R with the main indicators of effectiveness of BPH treatment: the structure of morbidity (prevalence of early BPH forms - groups 1 and 2), the number of surgical interventions, the frequency of complications (including surgical), general and specific costs for diagnosis and treatment of BPH. Conclusions. Acute urinary retention may be regarded as an integral indicator of the quality of care for patients with BPH.
Urologiia. 2016;(2):43-48
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Martov A.G., Ergakov D.V., Novikov A.B., Muzhetskaya N.G., Esen'yan G.L.


Introduction. The so-called stent-related symptoms caused mainly by detrusor overactivity due to distal ("cystic") curl of the internal stent are common among patients with this type of drainage. The need for long-term stenting makes the quality of life of cancer patients one of the challenging problems of modern urology. The aim of this study was to optimize treatment of stent-related symptoms in cancer patients with internal long-term stents by complementing the treatment regimen with m-anticholinergic solifenacin. Materials and methods. From November 2013 to November 2015 68 cancer patients (26 males, 42 females, age 36-79 years) underwent elective internal ureteral stenting for drainage of the upper urinary tract (UUT) with special long-term stents coated with the hydrogel. The urinary tract obstruction was caused by urological (24), gynecological (26) and colorectal (18) cancers. Before deciding on urinary tract drainage, all patients were treated with radiation or chemotherapy, 28 (41.2%) patients underwent surgery, but on admission all of them had contraindications to radical surgery for different reasons. In 52 (76.5%) patients UUT stenting was performed using transurethral access, in 12 (17.6%) by percutaneous access and in another 4 (5.9%) by the combined access with patients in the supine position. Percutaneous and combined access was used in cases of impracticability (failure) of transurethral stenting. Patients in group 1 (n=32) after stent placement received standard therapy co-administered with solifenacin 5 mg daily, group 2 (n=36) - only standard therapy. The data analyzed were the technical features of the internal drainage, optimal access and registered solifenacin-related adverse events. Control examinations were scheduled once in 3 months after stent placement according to the following algorithm: ultrasound scanning, laboratory test monitoring and, if indicated, plain urography. To objectify the severity of stent-related symptoms, a survey of patients using a special questionnaire was conducted. Visual analog scale was used to measure subjectively the patients’ condition. Results. After 12 months only 48 patients (26 from group 1 and 22 from group 2) completed the study. Follow-up examinations revealed that the patients in group 1 had significantly lower score of stent-related symptom severity and better ratings in visual analog scale. The greatest difference (1-2 points) was found in urgency and urinary frequency scores. The safety profile of solifenacin 5 mg corresponded to the findings of previous studies, there was no serious adverse events requiring discontinuation of the drug. Conclusions. Installing internal stents in UUT in cancer patients requires relevant experience in Roentgen-endoscopic operations using transurethral and percutaneous approaches and special equipment. In most cases, for preventing and eliminating supravesical obstruction in cancer patients, special internal stents for the long term placement are required. The add-on solifenacin therapy 5 mg/day resulted in almost 20% reduction in the severity of stent-related irritative symptoms and improved the quality of life in this extremely challenging category of patients.
Urologiia. 2016;(2):49-57
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Loran O.B., Veliev E.I., Seregin A.V., Khachatryan A.L., Guspanov R.I., Seregin I.V.


60 women, who underwent anterior pelvic exenteration with different types of urine derivation since 2004 till 2014 years in urology department, RMAPO, S.P. Botkin city hospital, were included in retrospective investigation. Middle age of patients was 53,2±3 (32-68). 38 women with bladder cancer and 22 women with urinary injuries after radiation therapy underwent anterior pelvic exenteration. Aim of this work is to perform quality of life comparison of patients after anterior pelvic exenteration with different types of urine derivation. Patients were divided in 3 groups: 1-st group 39 (65%) women, who underwent Bricker’s operation, 2-nd group 19 (31,66% ) women, who had Studer’s operation and 3-rd group - 2 (3,34%), patients who underwent continent urine derivation with formation of catheterizing urinary reservoir. Questionnaire (SF-36) was used to evaluate quality of life. Observation period was from 2 to 10 years. Postsurgical lethality was 3%, 5-years survival rate was 60,9±15,8% and 5-years recurrence-free survival rate was 55,4±12,6%. We established that quality of life in women who underwent orthotopic urine derivation was higher than in patients who underwent incontinent ileoconduit formation. Better quality oflife was demonstrated by women, who had catheterizing urinary reservoir, but it is difficult to compare this group with the others, because of small number of patients with heterotopic catheterizing reservoir. Regarding the results of our investigation we made next conclusions: • In spite of difficult technique, high risk of postoperative complications and lethality, anterior pelvic exenteration provide 5-years survival rate for 70% of patients • In locally advanced tumors of pelvic organs anterior pelvic exenteration is salvational operation and keep satisfactory quality of life • Orthotopic intestinal urine derivation is better to provide satisfactory quality of life for patients with invasive bladder cancer. • For women with urinary injuries after radiation therapy Briker’s operation is better type of urine derivation, in special cases heterotopic catheterizing reservoirs can be made.
Urologiia. 2016;(2):58-62
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Alyaev Y.G., Rapoport L.M., Enikeev M.E., Bezrukov E.S., Shpot’ E.V., Korolev D.O., Fokin I.V., Marisov L.V.


The problem of detecting localized prostate cancer following transurethral resection of the prostate (TURP) for benign prostatic hyperplasia is fairly common. Historically, radical prostatectomy (RP) after previously performed TURP was associated with poor surgical and functional outcomes. It is believed that the periprostatic fibrosis, scar tissue and inflammation after previous TURP may interfere with the optimal RP results. The present retrospective study evaluates intraoperative characteristics, postoperative oncological and functional outcomes of RP in patients with a history of TURP.
Urologiia. 2016;(2):63-66
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Naghiyev R.N., Imamverdiyev S.B., Sanly O.M.


Objective. Evaluation of retrospective results of treatment of patients with kidney cancer, who have undergone a laparoscopic or a retroperitoneoscopic radical nephrectomy. Materials and Methods. We have conducted a retrospective analysis of 185 patients with kidney tumour, who have undergone a laparoscopic or a retroperitoneoscopic radical nephrectomy during 2010-2015. Amongst the participants there were 116 men (62.7%) and 69 women (37.3%) aged 29-86 (average age of 58.1 years). 150 patients (81.1%) have performed radical nephrectomy by transperitoneal access, while 30 patients (16.2%) experienced identical process through retroperitoneal access. 5 cases (2.7%) hybrid technique was utilized. 97 patients performed nephrectomy on the right side, 88 patients on the left side. 178 patients (96.2%) had a single kidney tumours, while 7 (3.8%) had multiple tumours ranging between 2-8. 15 patients, who experienced a laparoscopic radical nephrectomy, had a thrombus in kidney vein (level 1 under Mayo classification). 1 patient had a thrombus in vena cava (level 2). Results. Only one of the patients suffered a fatal outcome. 12 patients (6.5%) had a conversion. The duration of operation ranged between 50-215 minutes (average of 104.3 minutes), time of insufflation ranged between 36-205 minutes (average of 96.2 minutes). Average intraoperative blood loss constituted 147.8 ml. Patients spent 2-18 days (average 4.1 days) in the hospital after the surgery. Conclusion. There is an obvious advantage to utilizing a laparoscopic or a retroperitoneoscopic intervention in order to treat kidney cancer. The process constitutes minimal invasiveness, low death rates, minimal intraoperative blood loss and fast rehabilitation of the patients. 72% of patients who have who have experienced surgical intervention, such as radical nephrectomy, spent only 3-4 days in the hospital.
Urologiia. 2016;(2):67-70
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Rolevich A.I.


Aim: To evaluate in a prospective study the results of transurethral resection (TUR) for non-muscle invasive bladder cancer (NMIBC) and analyze the prognostic factors for the detection of residual tumor to develop indications for this intervention. Materials and methods: The study included 111 patients with primary or recurrent NMIBC and intermediate or poor prognosis after visually radical TUR of the bladder. All patients underwent repeat TUR, which included a thorough cystoscopy, biopsy or TUR of all suspicious areas of the bladder, a deep biopsy of the area of the previous resection including the muscular layer. All prognostic tumor characteristics for assessing risk factors were available in 81 patients. Results: In total, repeat TUR resulted in the detection of 29/111 (26.1%) malignant tumors, while muscle-invasive cancer was diagnosed in 4/29 cases (3.6% of all included patients). The analysis of the relationship of residual tumor detection with various factors showed that the results of repeat TUR correlated with cystoscopic data at the repeat intervention and the degree of the tumor differentiation. Stratification of data depending on these factors revealed that in the absence of a visible tumor and G1, residual tumor was detected in 3.5% of cases, compared with 28.1% for the negative cystoscopy and G2-G3, and 52.6% for the positive cystoscopy regardless of G. Conclusions: Cystoscopy may be applied for selecting NMIBC patients with G1 differentiation for repeat TUR. In the absence of cystoscopic confirmation of tumor, the repeat TUR can be avoided.
Urologiia. 2016;(2):71-76
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Kul'chavenya E.V., Shevchenko S.Y., Brizhatyuk E.V.


Introduction. Chronic prostatitis is a prevalent urologic disease, but treatment outcomes are not always satisfactory. As a rule, chronic prostatitis results in chronic pelvic pain syndrome, significantly reducing the patient's quality of life. Material and methods. Open pilot prospective non-comparative study was conducted to test the effectiveness of extracorporeal shock wave therapy (ESWT) using Aries (Dornier) machine in patients with chronic prostatitis (CP) of IIIb category. A total of 27 patients underwent ESWL as monotherapy, 2 times a week for a course of 6 sessions. Exposure settings: 5-6 energy level (by sensation), the frequency of 5 Hz, 2000 pulses per session; each patient received a total energy up to 12000 mJ. per procedure. Results. Treatment results were evaluated using NIH-CPSI (National Institute of Health Chronic Prostatitis Symptom Index) upon completing the 3 week course of 6 treatments and at 1 month after ESWT. Immediately after the ESWT course positive trend was not significant: pain index decreased from 9.1 to 7.9, urinary symptom score remained almost unchanged (4.2 at baseline, 4.1 after treatment), quality of life index also showed a slight improvement, dropping from 7.2 points to 6.0. Total NIH-CPSI score decreased from 20.5 to 18.0. One month post-treatment pain significantly decreased to 3.2 points, the urinary symptom score fell to 2.7 points, the average quality of life score was 3.9 points. Conclusion. ESWT, performed on Aries (Dornier) machine, is highly effective as monotherapy in patients with category IIIb chronic prostatitis.
Urologiia. 2016;(2):77-81
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Martov A.G., Dutov S.V., Andronov A.S.


Introduction. Percutaneous nephrolithotripsy (PNL) is the recommended method of surgical treatment of kidney stones of size greater than 2 cm. Trends in the development of modern urology have been steadily toward less traumatic method to treat nephrolithiasis - minimally invasive PNL. The present work aimed to explore of the possibilities of one of the modern variants of minimally invasive PNL - ultra-mini-PNL in treating nephrolithiasis. Materials and methods. The study included 60 patients (mean age 45.6±7.2 years) with isolated kidney calculus, up to 2.0 cm or several stones with a total size of up to 2.5 cm. All patients were found to have 77 kidney stones, six of which had a size of 10 mm, 51 had a size of 11-15 mm and 20 had a size of 16-20 mm. 45% of patients had isolated renal pelvic stones and 28.3% had stones in the renal pelvis and lower calyx. All patients underwent ultra-mini-PNL using nephroscope size 7.5 Ch and tube size 12 Fr. Results. The average duration of surgery from the moment of the puncture of the pyelocaliceal system to installing the nephrostomy tube was 65.4 minutes. Complete clearance of stones after single-stage ultra-mini-PNL was observed in 80% of cases. Nephrostomy tube was removed on days 2-3. The average postoperative hospital stay was 5.1 days. The most common complication was postoperative exacerbation of pyelonephritis (13.3% of patients), successfully treated with conservative measures. There were no cases of postoperative bleeding, accompanied by anemia and needed a blood transfusion. Conclusion. Considering high effectiveness and low rate of complications of ultra-mini-PNL, it can be successfully used in treating nephrolithiasis among a wide group of patients.
Urologiia. 2016;(2):82-88
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Khakkulov E.B.


Aim.To identify typical sonographic semiotics of ureterohydronephrosis in children having importance in determining the severity of disease and the choice of treatment strategy in this category of patients. Material and methods. Sonographic images of the kidneys and urinary tract of 158 children with ureterohydronephrosis were examined. Unilateral and bilateral ureterohydronephrosis was found in 75 and 83 children, respectively. There were 100 (63.3%) boys and 58 (36.7%) girls. The age of patients ranged from 3 months to 14 years (mean 4.15+3.21). Results. Ultrasound examination enables the upper 193 (80.1%) and lower 167 (69.3%) third of ureters to be visualized. At the same time more than half of the visualized ureters had a diameter greater than 1 cm, and one-tenth of the affected ureters had diameters greater than 2 cm. If direct visualization of the ureters was impossible, pelvicalyceal system was evaluated, which was expanded on the affected side in all examined children. The morpho-sonographic changes of renal parenchymal in children with III-IV degree ureterohydronephrosis are described in details. Conclusion. Ultrasound examination can be regarded as a screening method for initial evaluation of patients with ureterohydronephrosis. It provides a rough estimation of the extent, level and nature of disturbances of urinary excretion, a preliminary assessment of the renal parenchyma and identification of anomalies of the urinary tract. These findings can be useful in choosing an optimal algorithm of diagnosis and surgical treatment of the disease.
Urologiia. 2016;(2):89-91
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Sokolov A.A., Martov A.G.


Globally, the number of patients with end-stage renal disease (ESRD) has been steadily increasing every year. These patients need renal replacement therapy which includes peritoneal dialysis, programmed hemodialysis and kidney transplantation, which is the ultimate form of replacement. Living donor kidney transplantation has significant advantages over cadaveric kidney transplantation regarding the long-term functional results of renal transplant and the survival of recipients. Open nephrectomy, previously used to retrieve a healthy kidney from a donor is associated with traumatic access and a long recovery period of the donor. With the development of minimally invasive technologies, laparoscopic living donor nephrectomy has been developed, which currently is the best method for retrieving transplant kidney. The review outlines the characteristics and outcomes of laparoscopic living donor nephrectomy for kidney transplantation.
Urologiia. 2016;(2):92-95
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Gilyazova I.R., Klimentova E.A., Pavlov V.N., Khusnutdinova E.K.


Small non-coding RNAs (microRNAs) are involved in almost all biological mechanisms of carcinogenesis. Due to their stability in biological fluids microRNAs may serve a perspective biomarker for diagnosis and prognosis of oncological diseases. The review is dedicated to the analysis of microRNAs, as potential diagnostic markers of urological malignancies. Recent advances in the knowledge of miRNAs origin in body fluids, their stability and application as a potentially new class of biomarkers in medicine are summarized and discussed in the article.
Urologiia. 2016;(2):96-103
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Guliev B.G., Komyakov B.K., Al-Attar T.K.


Aim. To analyze the results of surgical treatment of patients with long ureteral fibroepithelial polyps (FEP). Materials and Methods. From 2005 to 2014 three patients (1 man and 2 women) with large FEP were observed in our hospital. In 2 patients the base of the polyp was located in the proximal ureter and in 1 patient in the middle calyx of the single kidney. The fibroepithelial polyps were long and extended down to the lower third of the ureter (2) or protruded into the bladder (1). Endoscopic resection of the polyp was made in 1patient, resection of parenchyma in the middle calyx along with the base of FEP in 1 patient with the single kidney, and another patient underwent laparoscopic nephrectomy due to the absence of kidney function. Results. Endoscopic resection was successful; the operation lasted 45 minutes without complications. In the patients with a single right kidney operative time was 3.5 hours; during the operation, she received a blood transfusion. In the postoperative period, she underwent two hemodialysis sessions due to acute renal failure. Subsequently, her kidney function was restored. No FEP recurrences occurred in cases of organ sparing operations during follow-up. The postoperative period of the third patient submitted to laparoscopic nephrectomy was uneventful, creatinine levels remained in the normal range. Conclusion. For long, large ureteral FEPs with a broad base the choice of surgical option depends on possibility of tumor visualization and functional state of the kidney.
Urologiia. 2016;(2):104-108
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Davidov M.I.


The article reports a rare case of a 30 -year-old man with Hirschsprung's disease, who developed a giant fecalith in the rectum and sigmoid (weight 3.5 kg, the largest diameter 20 cm). The fecalith impaired urine flow by compressing urinary tract, thereby causing acute urinary retention and right-sided hydronephrosis with acute obstructive pyelonephritis. Removing fecalith resulted in the patient recovery and normal functioning of genitourinary system.
Urologiia. 2016;(2):109-111
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In Memory of Antonina Fedorovna Uchugina

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Urologiia. 2016;(2):112-112
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