Analysis of polylactide-based materials by raman spectroscopy

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Abstract

We present Raman study of a number of polylactide-based materials: polylactide stereoisomers, L-lactide oligomers, L-lactide/ε-caprolactone copolymers, and poly(L-lactide)/hydroxyapatite composites. It is established that the composition and crystallinity degree of a wide range of polylactide-based materials can be determined by Raman spectra. The advancement of this technique is crucial for the development of innovative polylactide-based materials used both for diverse medical applications and, for example, in the creation of biodegradable disposable packaging to address environmental pollution problems.

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About the authors

S. О. Liubimovskii

Prokhorov General Physics Institute of the RAS

Author for correspondence.
Email: liubimovskii@kapella.gpi.ru
ORCID iD: 0000-0002-9332-4359
Russian Federation, Moscow

V. S. Novikov

Prokhorov General Physics Institute of the RAS

Email: liubimovskii@kapella.gpi.ru
ORCID iD: 0000-0002-3304-1568

Cand.of Sciences (Phys.-Math.)

Russian Federation, Moscow

D. D. Vasimov

Prokhorov General Physics Institute of the RAS; Moscow Institute of Physics and Technology

Email: liubimovskii@kapella.gpi.ru
ORCID iD: 0009-0002-8105-0124
Russian Federation, Moscow; Moscow Region, Dolgoprudny

S. M. Kuznetsov

Prokhorov General Physics Institute of the RAS

Email: nikolaeva@kapella.gpi.ru
ORCID iD: 0000-0002-7669-1106

Cand.of Sciences (Phys.-Math.)

Russian Federation, Moscow

Е. V. Anokhin

Enikolopov Institute of Synthetic Polymeric Materials of the RAS

Email: nikolaeva@kapella.gpi.ru
ORCID iD: 0009-0005-2392-6994
Russian Federation, Moscow

А. V. Bakirov

Enikolopov Institute of Synthetic Polymeric Materials of the RAS

Email: nikolaeva@kapella.gpi.ru
ORCID iD: 0000-0003-0798-2791

Cand. of Sciences (Phys.-Math.)

Russian Federation, Moscow

К. Т. Kalinin

Enikolopov Institute of Synthetic Polymeric Materials of the RAS

Email: nikolaeva@kapella.gpi.ru
ORCID iD: 0000-0001-8838-5520
Russian Federation, Moscow

V. А. Demina

Enikolopov Institute of Synthetic Polymeric Materials of the RAS

Email: nikolaeva@kapella.gpi.ru
ORCID iD: 0009-0003-7302-1048

Cand.of Sciences (Phys.-Math.)

Russian Federation, Moscow

N. G. Sedush

Enikolopov Institute of Synthetic Polymeric Materials of the RAS

Email: nikolaeva@kapella.gpi.ru
ORCID iD: 0000-0002-6744-7662

Cand.of Sciences (Phys.-Math.)

Russian Federation, Moscow

S. N. Chvalun

Enikolopov Institute of Synthetic Polymeric Materials of the RAS

Email: nikolaeva@kapella.gpi.ru
ORCID iD: 0000-0001-9405-4509

Dr. of Sciences (Chem.), Corresponding Member of the RAS

Russian Federation, Moscow

М. N. Moskovskii

Federal Scientific Agronomic and Engineering Center VIM

Email: nikolaeva@kapella.gpi.ru
ORCID iD: 0000-0001-5727-8706

Dr. of Sciences (Tech.), prof. of the RAS

Russian Federation, Moscow

G. Yu. Nikolaeva

Prokhorov General Physics Institute of the RAS

Email: nikolaeva@kapella.gpi.ru
ORCID iD: 0000-0001-5979-9126

Cand.of Sciences (Phys.-Math.)

Russian Federation, Moscow

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2. Fig. 1. Raman spectra of the neat PLLA and their characteristics: a) with different CD in the range of 80–980 cm–1; b) dependence of the ratio of the peak intensities of the PLLA Raman bands at 411 and 874 cm–1 on CD, measured by X-ray diffraction analysis

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3. Fig. 2. Raman spectra of the LLA/CL copolymers with different compositions and their characteristics: a) in the range of 2 500–3 300 cm–1; b) dependence of the ratio of the peak intensity of the PLLA Raman band at 2 947 cm–1 to the sum of the peak intensities of this band and the PCL Raman band at 2 914 cm–1 on the molar content of LLA, measured by NMR spectroscopy

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4. Fig. 3. Raman spectra of PLLA, PDLA, and PDLLA (the ratio of the contents of D- and L-units is 50 : 50): a) range 80–1 410 cm–1; b) range 1 405–1 950 cm–1; c) range 2 575–3 200 cm–1

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5. Fig. 4. Raman spectra of LLA oligomers with 10, 40 and 100 lactic acid units, PLLA, toluene, and normal alkane C12H26 (n-dodecane): a) range 80–1 410 cm–1; b) range 1 405–1 950 cm–1; c) – range 2 575–3 200 cm–1

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6. Fig. 5. Raman spectra of the PLLA/HA composites with various compositions and their characteristics: a) in the range of 100–1 410 cm–1; b) dependence of the ratio of the peak intensities of the HA Raman band at 962 cm–1 and the PLLA Raman band at 874 cm–1 on the mass content of HA

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Copyright (c) 2025 Liubimovskii S.О., Novikov V.S., Vasimov D.D., Kuznetsov S.M., Anokhin Е.V., Bakirov А.V., Kalinin К.Т., Demina V.А., Sedush N.G., Chvalun S.N., Moskovskii М.N., Nikolaeva G.Y.