EFFECT OF SIMVASTATIN ON ENDOTHELIUM-DEPENDENT VASODILATATIONOF CEREBRAL VESSELS IN ANIMALS WITH STREPTOZOTOCIN-INDUCEDDIABETES MELLITUS
- Authors: Tyurenkov IN1, Voronkov A.V.1, Tyurenkov IN1, Voronkov AV1
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Affiliations:
- Issue: Vol 7, No 4 (2010)
- Pages: 87-89
- Section: Articles
- URL: https://journals.eco-vector.com/1994-9480/article/view/118205
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Abstract
It was revealed that administration of simvastatin prevents disorders in the NO-synthase system in cerebral vessels of animals with experimental diabetes. We can assume that endothelium-protective effect of simvastatin is associated with stabilization of NO-synthase system, which is manifested by an improvement of vasodilatating endothelial function and a decrease in the resistance and stiffness of the blood vessels in rats with hormonal disorders
About the authors
I N Tyurenkov
Andrey Vladislavovich Voronkov
Email: prohor.77@mail.ru <mailto:prohor.77@maii.ru>
I N Tyurenkov
A V Voronkov
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