Fixed combination of enalapril and hydrochlorothiazideas a drug for initial treatment of arterial hypertension


Cite item

Full Text

Abstract

The article is focused on the results of a six-month open non-comparative research of the fixed combination of
enalapril and hydrochlorothiazide (Enap-Н) which were given for initial treatment of arterial hypertension (AH). Antihypertensive
efficacy and Enap-Н ability to influence cardiovascular remodeling were studied in 25 high risk AH patients who
didn't receive drug therapy before. Research has shown high antihypertensive activity of the drug and its positive effect
on the heart and vessels remodeling. However, Enap-Н therapy caused significant increase of the uric acid level and this
condition demands controlling blood biochemical parameters in the course of drug therapy.

References

  1. Caro J.J., Speckman J.L., Salas M., et al. // CMAJ. - 1999. - Vol. 160, № 1. - P. 41-46.
  2. Chobanian A.V., Bakris G.L., Black H.R., et al. // JAMA. - 2003. - Vol. 289, № 19. - P. 2560-2572.
  3. Devereux R.B., Reichek N. // Circulation. - 1977. - Vol. 55. - P. 613-618.
  4. Guidelines Committee // J. Hypertens. - 2003. - Vol. 21. - P. 1011-1053.
  5. Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure // Arch. Intern. Med. - 1997. - Vol. 157. - P. 2413-2446.
  6. World Health Organization-International Society of Hypertension // J. Hypertens. - 1999. - Vol. 17. - P. 151-183.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2005 Ilyukhin O.V., Kalganova E.L., Lopatin Y.M., Kaplanov T.D., Ivanenko V.V., Каplanov Т.D., Ivanenko V.V., Ilyukhin O.V., Kalganova E.L., Lopatin Y.М.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 79562 от 27.11.2020 г.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies