Vol 3, No 1 (2006)
- Year: 2006
- Articles: 25
- URL: https://journals.eco-vector.com/1994-9480/issue/view/6010
Articles









Pathokinesis of venous cerebral blood circulationdisturbances
Abstract
Timely diagnosis of cerebral venous blood circulation disturbances plays an imporlani role in the management of cerebral vascular pathology. The objective of this work was to correlate the clinical and structural-functional data of cerebral venous ishaemia which at Neurology Department of Central Clinic of Tbilisi State Medical Universily and. Reseach Institute of Medical Radiology (neurology investigation, doppler ultrasound and neuroimaging of 833 patients).
Summing up the results of correlate comparison we conclude that sonography of cerebral vessels, supported by data of clinical and neuroimaging investigation can detect various disturbances of blood circulation.
Journal of Volgograd State Medical University. 2006;3(1):17-19



Efficiency of treatment of chronic heart failurewith basis medications in aged patients accordingto their renal functional condition
Abstract
Renal dysfunction in patients with post-infarction chronic heart failure (CHF) is associated with activation of sympathetic autonomic nervous system, with the increased number of patients with unfavourable type of remodeling of the heart. The efficiency of the therapy in elderly patients with CHF depends on the influence of basis treatment of CHF on the renal function.
Journal of Volgograd State Medical University. 2006;3(1):19-25



Diastolic disfunction in patientS with diaBetes mellitus type I: influence of disease duration and carbohydrate metabolism compensation
Abstract
Early diagnostics of diastolic dysfunction in patients with diabetes mellitus is of primary significance. The present paper evaluates the influence of compensation of carbohydrate metabolism in patients with diabetes mellitus type I on intracardiac haemodynamics. In 153 patients with the diabetes mellitus significant changes of intracardiac blood flow in diastole was revealed.
Journal of Volgograd State Medical University. 2006;3(1):25-28






Remote results of surgical treatment of acutevaricothrombophlebitis in the area of the greatsaphenous magna vein(quantitative and qualitative analysis)
Abstract
The quantitive and qualitative analysis of remote results of urgent radical phlebectomy for acute superficial thrombophlebitis, using CEAP classification and specific health-related quality of the life questionnaire for chronic venous insufficiency (CIVIQ), has been carried out. The results show that the proposed method, besides its high clinical efficiency, provides a marked life quality improvement; therefore it can be recommended as a method of the first choice for acute superficial varicothrombophlebitis management.
Journal of Volgograd State Medical University. 2006;3(1):32-38



Comparison of efficacy of surgery and medicationtreatment of patients with vertebro-basillaryinsufficiency
Abstract
The paper presents a comparative analysis of surgical and conservative methods of treatment of patients with vertebro-basillary insufficiency. Effectiveness of surgical treatment was demonstrated in 85% of patients under investigation.
Journal of Volgograd State Medical University. 2006;3(1):38-42



Effect of quinapril on endothelial disfunction of arteriesand functional condition of callicreine-kinine systemin patients with arterial hypertension
Abstract
The effect of quinapril on endothelial disfunction of arteries and functional condition of callicreine-kinine system in 38 patients with arterial hypertension was shown in the study. It was demonstrated that in patients with arterial hypertension endothelial disfunction is related to the changes in the system of the enzymatic cascade of bradikinine accumulation. The combined effect of studied indices on the developing endothelial disfunction in patients with arterial hypertension was significant. Estimation of prognostic value of changes in the callicreine-kinine system components in patients with arterial hypertension revealed that a decrease of precallicreine concentration in endothelial lesions is the most significant factor. In patients with arterial hypertension changes of vasodilating endothelium function were associated with the restoration of activity of callicreine-kinine system.
Journal of Volgograd State Medical University. 2006;3(1):41-45



Arterial hypertension in children and teenagerswith obesity and metabolic syndrome accordingto the results of daily blood pressure monitoring
Abstract
In the article it is shown, that occurrence of various forms of arterial hypertension (АH) in children with obesity and hypothalamic syndrome is associated with the degree of insulin resistance. "A white dressing gown" hypertension was registered 2,5 times more often among children with obesity without insulin resistance while liable and stable forms of AH - 2,8 times more often in children with a metabolic syndrome. It is necessary to include children with obesity and "a white dressing gown" АH, in the group of high risk of true АH development. In children and teenagers with metabolic syndrome and with AH stable forms marked changes of сircadian rhythm of the arterial pressure (AP) indicated a decrease in AP at night (nondippers) and a night hypertension (night-peakers). The data provide evidence of cardiovascular system failure in regulation of a vascular tone when accompanied by pronounced insulin resistance.
Journal of Volgograd State Medical University. 2006;3(1):45-49









On predictors of an acute course of gestational pyelonephritis
Abstract
The purpose of the research was to define some factors influencing the course of pyelonephritis in pregnancy. We have studied 95 pregnant patients with pyelonephritis. Clinical, microbiological and immunological methods of research have been used in examination of the patients. Distinctions in etiology of disease, parameters of cellular immune status, serum level of Interleukin-1-beta, Interleukin-8, Interleukin-4, Interleukin-10 and Interferon-gamma, colon bacterial microflora in pregnant patients with recurrent course of pyelonephritis were evaluated.
Journal of Volgograd State Medical University. 2006;3(1):51-55



justification of structure and antimicrobic activityof granules containing isoniazid and etambutolehydrochloride
Abstract
Research on development of the granules providing prolonged release of isoniazid and etambutole hydrochloride from a medical product was carried out for the purpose of improving the care of out-patients. During research the auxiliary substance and a dampener are chosen, the optimum structure of a medical product is developed.
Journal of Volgograd State Medical University. 2006;3(1):55-59









Factors effecting efficiency of medical aid and qualityof life in patients with epilepsy
Abstract
The results studing the factors affecting the effectiveness of qualified help to the epileptic patients, the revealed typical mistakes in treatment tactics, patients' quality of life, as well as testing neurologist on the questions of diagnostics and treatment of the epileptic patients made it possible to propose fundamental ways of reorganising the antiepileptic service with an orientation towards common European standards of health care to epileptic people.
Journal of Volgograd State Medical University. 2006;3(1):66-69



Morphological substantiation of preventionof periodontal inflammation with biological methodsof treatment of pulpitis
Abstract
The author of this article proposes biological methods of treatment of pulpitis as a preventive measure against inflammation in periodontal tissues. Comparative analysis of calcium-phosphate medications with different composition in treatment of experimental traumatic pulpitis with pulp protection in experimental animals (dogs) is provided. This investigation shows a high efficiency of medications comprising hydroxyapatite and tri-calcium-phosphate as a preventive measure against periodontal inflammation.
Journal of Volgograd State Medical University. 2006;3(1):69-72



Memory disorders in patients with ischemic insult during early reconstructive period
Abstract
170 patients with ischemic stroke with similar cognitive and educational levels were examined. Pharma-cotherapy with peptides and electrostimulation of the stroke directed to improvement of both memory and thinking were taken into consideration. Luria and Benton test, Meily test; evaluation of the audio-verbal, declarative, semantic, long-term kinds of memory were applied. It is shown that remembering of the new information concerning verbal names was worse in patients with mediobasal, frontal and temporal location of the stroke and depended on clinical manifestations of disorders.
Journal of Volgograd State Medical University. 2006;3(1):72-74



Markers of endotoxicosis and antioxidative defence system in experimental pancreonecrosis
Abstract
The objective of the research was to justify indications for application of antioxidants during experimental pancreonecrosis on the basis of estimation of intensity of lipid peroxidation processes and the condition of antioxidant system.
Erythrocytes, plasma, blood serum, tissues of pancreas and liver of dogs were used as substrates for the research. Ten healthy animals constituted the control group. The comparison groups were ten animals with the experimental pan-creonecrosis (12 hours for the 2nd group (5 dogs), 24 hours for the 3rd group (5 dogs). During all periods of the research in blood, tissues of pancreas and liver intensification of processes of lipid peroxidation and rise of the content of toxins of average molecular weight against a background of suppression of the antioxidant system were observed. In the liver tissue of the 3rd group dogs there was an increase of the glutathione content to initial level. A leading role of this organ in antioxidants supply by means of their synthesis and in lipid peroxidation regulation has been proved.
Journal of Volgograd State Medical University. 2006;3(1):74-77



Monoclonal antibodies against antigens of CoxiellaBurnetii: development, characteristics and perspectivesof application in laboratory diagnostics of Qu fever
Abstract
The collection of hybridomas (7 types) producing monoclonal antibodies (MA) by fusion of cells of mice myeloma of line P3-X63-Ag.653 and splenocytes of BAL/c mice, immunized with antigens of I-II phase of C.burnetii has been developed. MA are directed at different epitomes, located on the antigen complexes of Coxiella burnetii. The
characteristics of MA (specifity, activity) have been studied using ELISA and FIA; perspectives of their application for the laboratory diagnostics of QU fever are discussed.
Journal of Volgograd State Medical University. 2006;3(1):77-80











