CLINICAL AND DIAGNOSTICAL SIGNIFICANCE OF ENZYME ACTIVITY EVALUATIONOF THE PURINE METABOLISM ADENYLIC POOL IN LYMPHOCYTES AND RED BLOODCELLS OF PATIENTS WITH SYSTEMIC SCLERODERMA
- 作者: Zborovskiy AB1, Abramov NB1, Zborovski AB1, Abramov NB1
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隶属关系:
- 期: 卷 5, 编号 4 (2008)
- 页面: 71-74
- 栏目: Articles
- URL: https://journals.eco-vector.com/1994-9480/article/view/118021
- ID: 118021
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Significant decrease of adenine deaminase activity in erythrocytes and increase of adenosine deaminase and adenine
deaminase activities together with decrease of AMP-deaminase activity in lymphocytes of patients with systemic scleroderma
was discovered after the treatment course. Differences between all degrees of pathological process activity were demonstrated
to be significant. Evaluation of activity of the enzymes under investigation promoted more precise diagnostics of the degree of process activity and the control therapy efficiency in patients with systemic scleroderma.
deaminase activities together with decrease of AMP-deaminase activity in lymphocytes of patients with systemic scleroderma
was discovered after the treatment course. Differences between all degrees of pathological process activity were demonstrated
to be significant. Evaluation of activity of the enzymes under investigation promoted more precise diagnostics of the degree of process activity and the control therapy efficiency in patients with systemic scleroderma.
参考
- Девятаева Н. М. Клинико-диагностическое значение исследования активности 5'-нуклеотидазы, АМФ-дезаминазы, адениндезаминазы, аденозиндезаминазы в лизатах лимфоцитов, эритроцитов и плазмы крови больных системной красной волчанкой: диссертация канд. мед. наук. - Волгоград, 2005. - 226 с.
- Карпищенко А. И. Медицинские лабораторные технологии. Справочник. - СПб.: Интермедика, 2002. - 600 с. 3.
- Клинические рекомендации. Ревматология / Под ред.Е. Л. Насонова. - М.: ГЕОТАР-Медиа, 2005. - С. 168-185. 4.
- Subcommittee for scleroderma criteria of the American Rheumatism Associatiation Diagnostic and Therapeutic Criteria Committee: Prelinunary criteria for the classification of systemic sclerosis (scleroderma) // Arthritis Rheum. Ibid. - 1980. - № 23. - P. 581-590.
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