CLINICAL AND DIAGNOSTICAL SIGNIFICANCE OF ENZYME ACTIVITY EVALUATIONOF THE PURINE METABOLISM ADENYLIC POOL IN LYMPHOCYTES AND RED BLOODCELLS OF PATIENTS WITH SYSTEMIC SCLERODERMA
- Authors: Zborovskiy AB1, Abramov NB1, Zborovski AB1, Abramov NB1
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Affiliations:
- Issue: Vol 5, No 4 (2008)
- Pages: 71-74
- Section: Articles
- URL: https://journals.eco-vector.com/1994-9480/article/view/118021
- ID: 118021
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Abstract
Significant decrease of adenine deaminase activity in erythrocytes and increase of adenosine deaminase and adenine
deaminase activities together with decrease of AMP-deaminase activity in lymphocytes of patients with systemic scleroderma
was discovered after the treatment course. Differences between all degrees of pathological process activity were demonstrated
to be significant. Evaluation of activity of the enzymes under investigation promoted more precise diagnostics of the degree of process activity and the control therapy efficiency in patients with systemic scleroderma.
deaminase activities together with decrease of AMP-deaminase activity in lymphocytes of patients with systemic scleroderma
was discovered after the treatment course. Differences between all degrees of pathological process activity were demonstrated
to be significant. Evaluation of activity of the enzymes under investigation promoted more precise diagnostics of the degree of process activity and the control therapy efficiency in patients with systemic scleroderma.
References
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