Fixed combination of enalapril and hydrochlorothiazideas a drug for initial treatment of arterial hypertension


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The article is focused on the results of a six-month open non-comparative research of the fixed combination of
enalapril and hydrochlorothiazide (Enap-Н) which were given for initial treatment of arterial hypertension (AH). Antihypertensive
efficacy and Enap-Н ability to influence cardiovascular remodeling were studied in 25 high risk AH patients who
didn't receive drug therapy before. Research has shown high antihypertensive activity of the drug and its positive effect
on the heart and vessels remodeling. However, Enap-Н therapy caused significant increase of the uric acid level and this
condition demands controlling blood biochemical parameters in the course of drug therapy.

参考

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版权所有 © Ilyukhin O.V., Kalganova E.L., Lopatin Y.M., Kaplanov T.D., Ivanenko V.V., Каplanov Т.D., Ivanenko V.V., Ilyukhin O.V., Kalganova E.L., Lopatin Y.М., 2005

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