Relief of acute pain syndrome in the patient with spondylogenic dorsalgia


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Abstract

Dorsalgia (particularly, lumbalgia) is a serious medical problem with involvement of significant economic losses. We consider the possibility of non-steroidal anti-inflammatory drugs (NSAIDs) ketorolac administration, which is widely used in several countries for the relief of acute pain caused by various pathological conditions, in treatment of dorsalgia. According to numerous studies, ketorolac is an effective and sufficient safety drug for the treatment of acute lower dorsalgia. At least, it equal to other NSAIDs, in some cases surpassing their efficacy and tolerability. Comparable analgesic effect of ketorolac with opioids in the absence of many undesirable effects of the latter is also showed.

References

  1. Carey T, Evans A, Hadler N, et al. Acute severe low back pain. A population-based study of prevalence and care-seeking. Spine 1996;21:339-44.
  2. Luo X, Pietrobon R, Sun S, et al. Estimates and patterns of direct health care expenditures among individuals with back pain in the United States. Spine 2004;29:79-86.
  3. Bair M, Robinson R, Katon W, et al. Depression and pain comorbidity: a literature review. Arch Intern Med 2003;163:2433-45.
  4. Perez-Urizar J, Granados-Soto V, Castaneda-Hernandez G, et al. Analgesic efficacy and bioavailability of ketorolac in postoperative pain: a probability analysis. Arch Med Res 2000;31(2):191-96.
  5. Brown C, Moodie J, Wild V, et al. Comparison of intravenous ketorolac tromethamine and morphine sulfate in the treatment of postoperative pain. Pharmacotherapy 1990;10(6 ( Pt 2)):116S-121S.
  6. Dula D, Anderson R, Wood G. A prospective study comparing i.m. ketorolac with i.m. meperidine in the treatment of acute biliary colic. J Emerg Med 2001;20(2):121-24.
  7. Henderson S, Swadron S, Newton E. Comparison of intravenous ketorolac and meperidine in the treatment of biliary colic. J Emerg Med 2002;23(3):237-41.
  8. Barber F, Gladu D. Comparison of oral ketorolac and hydrocodone for pain relief after anterior cruciate ligament reconstruction. Arthroscopy 1998;14(6):605-12.
  9. Eberson C, Pacicca D, Ehrlich M. The role of ketorolac in decreasing length of stay and narcotic complications in the postoperative pediatric orthopaedic patient. J Pediatr Orthop 1999;19(5):688-92.
  10. Lieh-Lai M, Kauffman R, Uy H, et al. A randomized comparison of ketorolac tromethamine and morphine for postoperative analgesia in critically ill children. Crit Care Med 1999;27(12):2786-91.
  11. Veenema K, Leahey N, Schneider S. Ketorolac versus meperidine: ED treatment of severe musculoskeletal low back pain. Am J Emerg Med 2000;18(4):40404-07.
  12. Верткин А.Л., Прохорович Е.А., Горулева Е.А. и др. Эффективность и безопасность применения Кеторола для купирования болевого синдрома на догоспитальном этапе // Неотложная терапия. 2004. Т. 1-2. № 16-17. С. 12-17.
  13. Шостак Н.А., Правдюк Н.Г., Аксенова А.В. и др. Возможности оптимизации анальгетической и противовоспалительной терапии у больных с острым болевым синдромом в спине // РМЖ. Ревматология. 2006. Т. 14. № 8. С. 610-615.

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