NEW POTENTIALS FOR PREDICTION AND EVALUATION OF THE EFFECTIVENESS OF TREATMENT OF IRON DEFICIENCY ANEMIA


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Abstract

This study was aimed to development of prognostic criteria for efficacy of treatment of iron deficiency anemia based on erythrocyte indices and causes of anemia. For the purpose of assess the effectiveness of therapy of iron deficiency anemia (IDA), authors have analyzed results of a survey of 60 patients (9 men, 51 women, including nine pregnant women), treated by hematologist. Three prognostic factor of efficacy of treatment of IDA were defined. The treatment is ineffective in case of combined pathology of female reproductive system and gastrointestinal tract, no significant decrease in red count in peripheral blood, depression of red cell lineage of the bone marrow. The hemoglobin level is not a prognostic factor in the treatment of IDA. The transfusion therapy with erythrocyte concentrate or administration of recombinant erythropoietin in relation to the severity of patient's condition is required in patients with severe IDA or in the case of ineffective therapy with iron supplements. Correction of erythrocyte indices should be carried out even in case of with minimal decrease of hemoglobin level in all pregnant women.

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