ARTERIAL HYPERTENSION IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

The article presents the results of evaluation of frequency of occurrence and characteristics of arterial hypertension (AH) in 230 patients with chronic obstructive pulmonary disease (COPD). 60 men with essential arterial hypertension, matched by age to the examined patients with COPD were included in comparison group. The results of the analysis indicate a higher detection rate of arterial hypertension, as well as a higher average systolic and diastolic blood pressure (BP) in different age groups in patients with COPD compared with the general population, suggesting the COPD as a risk factor for arterial hypertension. In contrast to the patients with essential arterial hypertension, family history is not typical for patients with COPD and AH, and the incidence of overweight and obesity is lower than in the general population. Pathological types of diurnal blood pressure curve are dominated in patients with COPD and characterized primarily by the insufficient degree of nocturnal BP reduction, which is apparently due to the fact that during sleep such patients have periods of hypoxemia and hypercapnia, leading to activation of neurohumoral activation. It should be noted that COPD patients without arterial hypertension have a tendency to a lack of nocturnal decrease in blood pressure. Apparently, this indicates that obstructive pulmonary disease may interfere with the normal circadian rhythm of blood pressure.

chronic obstructive pulmonary disease, arterial hypertension, 24-hour blood pressure monitoring