ОМЕГА-3-ПОЛИНЕНАСЫЩЕННЫЕ ЖИРНЫЕ КИСЛОТЫ: НА ПУТИ К СТАТУСУ САМОСТОЯТЕЛЬНОЙ СТРАТЕГИИ УЛУЧШЕНИЯ СЕРДЕЧНО-СОСУДИСТОГО ПРОГНОЗА
- Авторы: Фомин В.В.1, Fomin VV2
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Учреждения:
- ГОУ ВПО Первый МГМУ им. И.М. Сеченова Минздравсоцразвития России
- Выпуск: № 14 (2011)
- Страницы: 42-45
- Раздел: Статьи
- URL: https://journals.eco-vector.com/2073-4034/article/view/278971
- ID: 278971
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Аннотация
Представлены результаты клинических исследований, в которых изучалась возможность дополнительного влияния антигиперлипидемических препаратов (статинов, полиненасыщенных жирных кислот) на прогноз больных хронической сердечной недостаточностью (ХСН). Показана роль ω-3 полиненасыщенных жирных кислот в профилактике сердечно-сосудистых осложнений, в частности желудочковых аритмий и внезапной смерти у больных ХСН, а также ишемической болезнью сердца.
Об авторах
Виктор Викторович Фомин
ГОУ ВПО Первый МГМУ им. И.М. Сеченова Минздравсоцразвития РоссииГОУ ВПО Первый МГМУ им. И.М. Сеченова Минздравсоцразвития России
V V Fomin
Список литературы
- Kjekshus J, Apetrei E, Barrios V, et al. CORONA Group. Rosuvastatin in older patients with systolic heart failure. N Engl J Med 2007;357(22):2248-61.
- Gissi-HF Investigators, Tavazzi L, Maggioni AP, Marchioli R, et al. Effect of rosuvastatin in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trial. Lancet 2008;372(9645):1231-39.
- McMurray JJ, Kjekshus J, Gullestad L, et al. CORONA Study Group. Effects of statin therapy according to plasma high-sensitivity C-reactive protein concentration in the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA): a retrospective analysis. Circulation 2009;120(22):2188-96.
- Cleland JG, McMurray JJ, Kjekshus J, et al. CORONA Study Group. Plasma concentration of amino-terminal pro-brain natriuretic peptide in chronic heart failure: prediction of cardiovascular events and interaction with the effects of rosuvastatin: a report from CORONA (Controlled Rosuvastatin Multinational Trial in Heart Failure). J Am Coll Cardiol 2009;54(20):1850-59.
- De Caterina R, Madonna R, Zucchi R, La Rovere MT. Antiarrhythmic effects of omega-3 fatty acids: from epidemiology to bedside. Am. Heart J 2003;146(3):420-30.
- Gissi-HF Investigators, Tavazzi L, Maggioni AP, Marchioli R, et al. Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trial. Lancet 2008;372(9645):1223-30.
- Ghio S, Scelsi L, Latini R, et al.; GISSI-HF investigators. Effects of n-3 polyunsaturated fatty acids and of rosuvastatin on left ventricular function in chronic heart failure: a substudy of GISSI-HF trial. Eur. J. Heart Fail 2010;12(12):1345-53.
- Finzi AA, Latini R, Barlera S, et al. Effects of n-3 polyunsaturated fatty acids on malignant ventricular arrhythmias in patients with chronic heart failure and implantable cardioverter-defibrillators: A substudy of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Insufficienza Cardiaca (GISSI-HF) trial. Am. Heart J 2011;161(2):338-43.
- Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico. Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Lancet 1999;354(9177):447-55.
- Marchioli R, Barzi F, Bomba E, et al.; GISSI-Prevenzione Investigators. Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: time-course analysis of the results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI)-Prevenzione. Circulation 2002;105(16):1897-903.
- Marchioli R, Marfisi R.M, Borrelli G, et al. Efficacy of n-3 polyunsaturated fatty acids according to clinical characteristics of patients with recent myocardial infarction: insights from the GISSI-Prevenzione trial. J Cardiovasc Med (Hagerstown) 2007;8 Suppl 1:34-7.
- Aarsetøy H, Pönitz V, Nilsen OB, et al. Low levels of cellular omega-3 increase the risk of ventricular fibrillation during the acute ischaemic phase of a myocardial infarction. Resuscitation 2008;78(3):258-64.
- Aarsetoey H, Aarsetoey R, Lindner T, et al. Low levels of the omega-3 index are associated with sudden cardiac arrest and remain stable in survivors in the subacute phase. Lipids 2011;46(2):151-61.
- Moertl D, Hammer A, Steiner S, et al. Dose-dependent effects of omega-3-polyunsaturated fatty acids on systolic left ventricular function, endothelial function, and markers of inflammation in chronic heart failure of nonischemic origin: a double-blind, placebo-controlled, 3-arm study. Am. Heart J 2011;161(5):915-19.
- Richardson ES, Iaizzo PA, Xiao YF, Electrophysiological mechanisms of the anti-arrhythmic effects of omega-3 fatty acids. J Cardiovasc Transl Res 2011;4(1):42-52.
- Streppel MT, Ocké MC, Boshuizen HC, et al. Long-term fish consumption and n-3 fatty acid intake in relation to (sudden) coronary heart disease death: the Zutphen study. Eur Heart J 2008;29(16):2024-30.
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