“Slozhnaya” bronkhial'naya astma - sovremennoe sostoyanie problemy


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Abstract

“Complicated" bronchial asthma (BA) is a serious medical and social problem associated with high morbidity and mortality, and amounts of up to 80 % of all health care costs for the treatment of BA. Understanding the immunological and pathogenic features of the disease led to the identification of different BA phenotypes and confirmed the need for expanding the choice of available therapeutic approaches. The results of the study involving 25 patients with uncontrolled severe atopic asthma showed that combination therapy (inhaled corticosteroids/ long-acting β2-agonists + montelukast 10 mg) for 24 weeks significantly optimizes clinical and functional control of the disease, and partly improves control of airway inflammation.

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