Personifitsirovannoe lechenie bol'nykh s sindromom slabosti sinusovogo uzla na osnove individual'nykh osobennostey genotipa


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Abstract

The distribution of genotype and allele frequencies of 4a/4b eNOS gene polymorphism in patients with idiopathic sick sinus syndrome (men, women, probands) compared with the control group was analyzed. Significant predominance of homozygous genotype for a rare 4b allele in all study subgroups was reported. Recommendations for the choice of drug therapy depending on the genotype were discussed.

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References

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