Prognosticheskaya tsennost' testa 30-sekundnoy zaderzhki dykhaniya v diagnostike maskirovannoy arterial'noy gipertenzii u lits molodogo vozrasta


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Abstract

Masked arterial hypertension (MAH) is often observed in young people who have no clinical signs of cardiovascular disease, and is accompanied by end-organ damages to the same extent as a stable arterial hypertension (SAH). For the diagnosis or exclusion of MAH in individuals without obvious signs of arterial hypertension, a sensitive, specific and cost-effective test is required. The present study has evaluated the hypertensive reaction to 30-second arbitrary breath-holding (breath-holding test) in 269 young subjects with no evidence of cardiovascular diseases. Of 269 normotensive subjects with office BP <140/90 mm Hgб53 had a positive test results, and 34 (12.6%) were diagnosed with MAH confirmed by positive results of 24-hour blood pressure monitoring. None of the 201 people with negative results of breath-holding test had MAH as confirmed by 24-hour blood pressure monitoring. The results of the pressor response to the breath-holding test and 24-hour blood pressure monitoring were in line in 93% of cases, and false-negative test results were absent. Breath-holding test can be used effectively to exclude MAH in healthy individuals and to identify individuals with MAH who require further examination and observation.

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