Laboratornye kriterii diagnostiki gipogonadizma u muzhchin
- Authors: Novikova E.G1, Selyatitskaya V.G1, Vasil'eva O.V1, Mitrofanov I.M1
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- Issue: No 12 (2015)
- Pages: 41-44
- Section: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/288080
- ID: 288080
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Abstract
This article discusses the criteria for diagnosis, individual normal values of testosterone and hormone replacement therapy monitoring. It is shown that the individual variability of of serum total testosterone in men differs in time by several folds (the coefficient of variation varies from 5.2 to 29.6%). Variability of the total testosterone level depends on the patient age and the presence of clinical signs of hypogonadism. These facts are of importance in the application of individual approach to the treatment of men with sympto-matic androgen deficiency, and should be considered when evaluating the effectiveness of testosterone replacement therapy.
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About the authors
E. G Novikova
Email: rmdc.nsk@gmail.com
V. G Selyatitskaya
O. V Vasil'eva
I. M Mitrofanov
References
- Калинченко С. Ю., Тюзиков И.А. Практическая андрология. М., 2009.
- Huhtaniemi I., Forti G. Male late-onset hypogonadism: pathogenesis, diagnosis and treatment. Nat. Rev. Urol. 2011;8(6):335-44.
- Dohle G.R., Arves S., Bettocchi C., Kliesch S., Punab M., de Ronde W. Guidelines on Male Hypogonadism. European Association of Urology, Guidelines. 2014 edition.
- Lunenfeld B.,Mskhalaya G.,Zitzmann M.,Arver S., Kalinchenko S., Tishova Y., Morgentaler A. Recommendations on the diagnosis, treatment and monitoring of hypogonadism in men. Aging. Male. 2015;18(1):5-15.
- Sattler F.R., He J., Chukwuneke J., Kim H., Stewart Y., Colletti P., Yarasheski K., Buchanan T. Testosterone supplementation improves carbo-hydrate and lipid metabolism in some older men with abdominal obesity. J. Gerontol. Geriatr. Res. 2014;3(3):1000159
- Novikova E., Selyatitskaya V., Mitrofanov I., Pinkhasov B., Karapetyan A. Association of erectile dysfunction and hypogonadism with metabolic syndrome in men with lower urinary tract symptoms of younger and older age groups. Advanc. Sex. Med. 2014;4:55-64.
- Lunglmayr G. Long-term therapy with a depot luteinizing hormone-releasing hormone analogue. J. Urol. 1998;140(4):775-77.
- Wang C., Nieschlag E., Swerdloff R., Behre H.M., Hellstrom W.J., Gooren L.J., Kaufman J.M., Legros J.J., Lunenfeld B., Morales A., Morley J.E., Schulman C., Thompson I.M., Weidner W., Wu F.C. Investigation, treatment, and monitoring of Late-Onset Hypogonadism in males: ISA, ISSAM, EAU, EAA, and ASA Recommendations. Eur. J. Endocrinol. 2008;159:507-14.
- Новикова Е.Г., Селятицкая В.Г, Лутов Ю.В. и соавт. Связь гипогонадизма с метаболическим синдромом у мужчин разных возрастных групп. Вестник НГУ. 2012; 10(1):54-62.
- Ullah M.I., Riche D.M., Koch C.A. Transdermal testosterone replacement therapy in men. Drug Des. Develop. Ther. 2014;8:101-12.
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