Laboratornye kriterii diagnostiki gipogonadizma u muzhchin


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This article discusses the criteria for diagnosis, individual normal values of testosterone and hormone replacement therapy monitoring. It is shown that the individual variability of of serum total testosterone in men differs in time by several folds (the coefficient of variation varies from 5.2 to 29.6%). Variability of the total testosterone level depends on the patient age and the presence of clinical signs of hypogonadism. These facts are of importance in the application of individual approach to the treatment of men with sympto-matic androgen deficiency, and should be considered when evaluating the effectiveness of testosterone replacement therapy.

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