The use of modified autografts for plastic closure of laryngotracheal defects: an experimental study


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Abstract

Background. The article presents the results of own authors’experimental and clinical studies using modified autografts for plastic closure of laryngotracheal defects (LTD). Objective. The development and implementation of a new method of plastic surgery for LTD using an erbium laser-molded costal autocartilage. Methods. As the first part of this work (2014-2016), an experimental study was conducted on 10 laboratory chinchilla rabbits. In the experiment, the selection of optimal safe modes of exposure to cartilage tissue was carried out. The obtained experimental data made it possible to develop a new methodology for plastic closure of LTD. In order to solve the task of developing a methodology for creating a strong frame material for plastic closure of the larynx and trachea defect, 10 patients with extensive LTD underwent surgery using a molded costal cartilage. Conclusion. Thus, the developed and experimentally substantiated technique of LTD plastic surgery makes it possible to restore the anatomical integrity of the respiratory tract, to ensure the functional consistency and anatomical shape of the lumen of the larynx and trachea, to prevent lysis of the cartilage autograft and pathological flotation of the newly formed front wall of the larynx and trachea in the long-term postoperative period.

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V. M Svistushkin

Sechenov First Moscow State Medical University (Sechenov University)

Clinic for of the Ear, Nose and Throat Diseases Moscow, Russia

S. V Starostina

Sechenov First Moscow State Medical University (Sechenov University)

Clinic for of the Ear, Nose and Throat Diseases Moscow, Russia

Liliya V. Selezneva

Sechenov First Moscow State Medical University (Sechenov University)

Email: lily.selezneva@gmail.com
Clinic for of the Ear, Nose and Throat Diseases; Cand. Sci. (Med.), Teaching Assistant at the Department of Ear, Nose and Throat Diseases 8/2, Trubetskaya str., Moscow 119991, Russian Federation

O. I Baum

Federal Research Center “Crystallography and Photonics" RAS

Institute of Photonic Technologies Moscow, Russia

E. N Sobol

Federal Research Center “Crystallography and Photonics" RAS

Institute of Photonic Technologies Moscow, Russia

Yu. M Aleksandrovskaya

Federal Research Center “Crystallography and Photonics" RAS

Institute of Photonic Technologies Moscow, Russia

A. V Starostin

Sechenov First Moscow State Medical University (Sechenov University)

Department of Faculty Surgery № 1 Moscow, Russia

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