Herniated disc resorption: a review of studies


Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Рұқсат ақылы немесе тек жазылушылар үшін

Аннотация

Currently, about a third of the population experiences back and neck pain. In this case, the most common cause is herniated interver-tebral discs (HIVD). Surgical treatment in the absence of severe neurological symptoms shows similar results with conservative ones, while in some patients the pain syndrome persists or recurs after surgery. Neuroimaging studies demonstrate the possibility of HIVD resorption in patients receiving conservative therapy. This article analyzes studies on resorption or regression of HIVD and the contributing factors. It has been shown that the large size of the HIVD, the age of 40-50 years, as well as the protrusion of disc tissues through the posterior longitudinal ligament, the presence of a free fragment (sequester) or MRI parameters (hyperintense signal in T2-weighted images; thickening of the gadolinium rim on contrast-enhanced MRI) remain favorable factors contributing to the HIVD regression. Currently, the incidence of resorption is 63%, and its time varies from 8.5 to 24 months. It was concluded that further research in order to better understanding of the HIVD regression mechanisms, search for regression markers, and search for methods stimulating this process is required.

Толық мәтін

Рұқсат жабық

Авторлар туралы

A. Tkachev

Dr. Berezin Medical Institute; Tkachev Clinic, Volgograd

Email: tkachevclinic@mail.iu

A. Epifanov

Tkachev Epifanov Clinic, Moscow

E. Akarachkova

International Society “Stress under Control"

I. Gordeeva

Dr. Berezin Medical Institute; Tkachev Clinic, Volgograd

Әдебиет тізімі

  1. Hoy D, Bain C, Williams G, et al. A systematic review of the global prevalence of low back pain. Arth Rheum. 2012;64(6):2028-37. doi: 10.1002/art.34347.
  2. Schmidt C.O, Raspe H, Pfingsten M, et al. Back pain in the German adult population: prevalence, severity, and sociodemographic correlates in a multiregional survey. Spine (Phila Pa 1976). 2007;32(18):2005-11. doi: 10.1097/BRS.0b013e318133fad8.
  3. Oliveira C.B, Maher C.G., Pinto R.Z., et al. Clinical practice guidelines for the management of nonspecific low back pain in primary care: an updated overview. Eur Spine J. 2018;27(11):2791-803. doi: 10.1007/s00586-018-5673-2.
  4. Hanvigsen J., Hancock M.J., Kongsted A., et al. What low back pain is and why we need to pay attention. Lancet. 2018;391(10137):2356-67. Doi:10.1016/ S0140-6736(18)30480-X.
  5. Kim R, Wiest C., Clark K., Cook C., Horn M. Identifying risk factors for first-episode neck pain: A systematic review. Musculoskelet Sci Pract. 2018;33:77-83. doi: 10.1016/j.msksp.2017.11.007.
  6. Blyth EM., Briggs A.M., Schneider C.H., et al. The Global Burden of Musculoskeletal Pain-Where to From Here? Am J Public Health. 2019;109(1):35-40. doi: 10.2105/AJPH.2018.304747.
  7. Heider EC, Mayer H.M. Operative Therapie des lumbalen Bandscheibenvorfalls [Surgical treatment of lumbar disc herniation]. Oper Orthop Traumatol. 2017;29(1):59-85. doi: 10.1007/s00064-016-0467-3.
  8. Кадырова Л.Р, Акарачкова Е.С., Керимова КС. и др. Мультидисциплинарный подход к пациенту с хронической болью. Русский медицинский журнал. 2018;7:28-32. [Kadyrova L.R., Akarachkova E.S., Kerimova KS, et al. Multidisciplinary approach to patient with chronic pain. Russkii meditsinskii zhurnal. 2018;7:28-32. (In Russ.)].
  9. Голубенко Е.О., Силина Е.В., Орлова А.С. Персонифицированный подход в лечении болевых синдромов. Современная наука: актуальные проблемы теории и практики. Серия: Естественные и технические науки. 2017;7-8:107-12
  10. McCulloch J.A. Focus issue on lumbar disc herniation: macro- and microdiscectomy. Spine (Phila Pa 1976). 1996;21(Suppl. 24):S45-56. doi: 10.1097/00007632-199612151-00005.
  11. Hoy D., March L., Brooks P, et al. The global burden of low back pain: estimates from the Global Burden of Disease 2010 study Ann Rheum Dis. 2014;73(6):968-74. Doi: 10.1136/ annrheumdis-2013-204428.
  12. Brinjikji W, Luetmer PH., Comstock B., et al. Systematic literature review of imaging features of spinal degeneration in asymptomatic populations. AJNR. Am J Neuroradiol. 2015;36(4):811-16. doi: 10.3174/ajnr.A4173.
  13. Al Qaraghli M.I., De Jesus O. Lumbar Disc Herniation. 2020Aug 10. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020. PMID: 32809713.
  14. Weinstein J.N., Lurie J.D., Tosteson T.D., et al. Surgical vs nonoperative treatment for lumbar disk herniation: the Spine Patient Outcomes Research Trial (SPORT) observational cohort. JAMA. 2006;296(20):2451-59. doi: 10.1001/jama.296.20.2451.
  15. Vroomen PC., de Krom M.C., Knottnerus J.A. Predicting the outcome of sciatica at short-term follow-up. Br J Gen Pract. 2002;52(475):119-23.
  16. Coste J., Delecoeuillerie G., Cohen de Lara A., et al. Clinical course and prognostic factors in acute low back pain: an inception cohort study in primary care practice. BMJ. 1994;308(6928):577-80. doi: 10.1136/bmj.308.6928.577.
  17. van den Hoogen H.J., Koes B.W., Deville W., et al. The prognosis of low back pain in general practice. Spine. (Phila Pa 1976). 1997;22(13):1515-21. doi: 10.1097/00007632-199707010-00019.
  18. Deyo R.A., Weinstein J.N. Low back pain. N Engl J Med. 2001;344(5):363-70. Doi: 10.1056/ NEJM200102013440508.
  19. Mixter W.J., Barr J.S. Rupture of the intervertebral disc with the involvement of the spinal canal. N Engl J Med. 1934;211:210-14.
  20. Atlas S.J., Keller R.B., Wu Y.A., et al. Long-term outcomes of surgical and nonsurgical management of lumbar spinal stenosis: 8 to 10 year results from the maine lumbar spine study Spine. (Phila Pa 1976). 2005;30(8):936-43. doi: 10.1097/01. brs.0000158953.57966.c0
  21. Lurie J.D., Tosteson T.D., Tosteson A.N., et al. Surgical versus nonoperative treatment for lumbar disc herniation: eight-year results for the spine patient outcomes research trial [published correction appears in Spine (Phila Pa 1976). 2015 Jan;40(1):E59]. Spine. (Phila Pa 1976). 2014;39(1):3-16. doi: 10.1097/BRS.0000000000000088.
  22. Peul W.C., van den Hout W.B., Brand R., et al; Leiden-The Hague Spine Intervention Prognostic Study Group. Prolonged conservative care versus early surgery in patients with sciatica caused by lumbar disc herniation: two year results of a randomised controlled trial. BMJ. 2008;336(7657):1355-58. doi: 10.1136/bmj.a143
  23. Davis R.A. A long-term outcome analysis of 984 surgically treated herniated lumbar discs. J Neurosurg. 1994;80(3):415-21. Doi: 10.3171/ jns.1994.80.3.0415.
  24. Haro H. Translational research of herniated discs: current status of diagnosis and treatment. J Orthop Sci. 2014;19(4):515-20. doi: 10.1007/s00776-014-0571-x.
  25. Key J.A. Intervertebral Disk Lesions are the Most Common Cause of Low Back Pain with or Without Sciatica. Ann Surg. 1945;121(4):534-39. doi: 10.1097/00000658-194504000-00013.
  26. Guinto F.C., Hashim H., Stumer M. CTdemonstration of disk regression after conservative therapy. AJNR. Am. J Neuroradiol. 1984;5(5):632-33.
  27. Ткачев А.М., Епифанов А.В., Акарачкова Е.С. и др. Патофизиологические аспекты резорбции грыж межпозвонкового диска. Consilium Medicum. 2019;21(2):59-63. [Tkachev A.M., Epifanov A.V., Akarachkova E.S., et al. Pathophysiologic aspects of resorption of intervertebral disk hernia. Consilium Medicum. 2019;21(2):59-63. (In Russ.)].
  28. Macki M., Hernandez-Hermann M., Bydon M., et al. Spontaneous regression of sequestrated lumbar disc herniations: Literature review. Clin Neurol Neurosurg. 2014;120:136-41. Doi: 10.1016/j. clineuro.2014.02.013.
  29. Hakan T., GUrcan S. Spontaneous Regression of Herniated Lumbar Disc with New Disc Protrusion in the Adjacent Level. Case Rep Orthop. 2016;2016:1538072. doi: 10.1155/2016/1538072.
  30. Maigne J.Y, Rime B., Deligne B. Computed tomographic follow-up study of forty-eight cases of nonoperatively treated lumbar intervertebral disc herniation. Spine. (Phila Pa 1976). 1992;17(9):1071-74. doi: 10.1097/00007632199209000-00010.
  31. Ahn S.H., Ahn M.W., Byun W.M. Effect of the transligamentous extension of lumbar disc herniations on their regression and the clinical outcome of sciatica. Spine. (Phila Pa 1976). 2000;25(4):475-80. doi: 10.1097/00007632-200002150-00014.
  32. Autio R.A., Karppinen J., Niinimaki J., et al. Determinants of spontaneous resorption of intervertebral disc herniations. Spine. (Phila Pa 1976). 2006;31(11):1247-52. doi: 10.1097/01. brs.0000217681.83524.4a.
  33. Komori H., Shinomiya K., Nakai O., et al. The natural history of herniated nucleus pulposus with radiculopathy Spine. (Phila Pa 1976). 1996;21(2):225-29. doi: 10.1097/00007632199601150-00013.
  34. Sakai T, Tsuji T., Asazuma T., et al. Spontaneous resorption in recurrent intradural lumbar disc herniation. Case report. J Neurosurg Spine. 2007;6(6):574-78. doi: 10.3171/spi.2007.6.6.11.
  35. Yamashita K., Hiroshima K., Kjjrata A. Gadolinium-DTPA-enhanced magnetic resonance imaging of a sequestered lumbar intervertebral disc and its correlation with pathologic findings. Spine. (Phila Pa 1976). 1994;19(4):479-82. doi: 10.1097/00007632-199402001-00021.
  36. Komori H., Okawa A., Haro H., et al. Contrast-enhanced magnetic resonance imaging in conservative management of lumbar disc herniation. Spine. (Phila Pa 1976). 1998;23(1):67-73. doi: 10.1097/00007632-199801010-00015.
  37. Splendiani A., Puglielli E., De Amicis R., et al. Spontaneous resolution of lumbar disk herniation: predictive signs for prognostic evaluation. Neuroradiol. 2004;46(11):916-22. doi: 10.1007/s00234-004-1232-0.
  38. Smirnova А., Tkachev А., Archakov D., et al. Resorption of a herniated disc. Stages of development and associated visual «effects» in MRI diagnosis Congress: ECR 2020. Poster Number: C-11869. doi: 10.26044/ecr2020/C-11869.
  39. Matsui Y, Maeda M., Nakagami W., Iwata H. The involvement of matrix metalloproteinases and inflammation in lumbar disc herniation. Spine. (Phila Pa 1976). 1998;23(8):863-69. doi: 10.1097/00007632-199804150-00005.
  40. Ozaki S., Muro T., Ito S., Mizushima M. Neovascularization of the outermost area of herniated lumbar intervertebral discs. J Orthop Sci. 1999;4(4):286-92. doi: 10.1007/s007760050105.
  41. Henmi T, Sairyo K., Nakano S., et al. Natural history of extruded lumbar intervertebral disc herniation. J Med Invest. 2002;49(1-2):40-3.
  42. Kato T, Haro H., Komori H., Shinomiya K. Sequential dynamics of inflammatory cytokine, angiogenesis inducing factor and matrix degrading enzymes during spontaneous resorption of the herniated disc. J Orthop Res. 2004;22(4):895-900. Doi: 10.1016/j. orthres.2003.11.008.
  43. Haro H., Kato T., Komori H., et al. Vascular endothelial growth factor (VEGF)-induced angiogenesis in herniated disc resorption. J. Orthop Res. 2002;20(3):409-15. doi: 10.1016/S0736-0266(01)00150-4.
  44. Yasuma T, Arai K., Yamauchi Y The histology of lumbar intervertebral disc herniation. The significance of small blood vessels in the extruded tissue. Spine. (Phila Pa 1976). 1993;18(13):1761-65. doi: 10.1097/00007632-199310000-00008.
  45. Ito T., Yamada M., Ikuta F, et al. Histologic evidence of absorption of sequestration-type herniated disc. Spine. (Phila Pa 1976). 1996;21(2):230 34. doi: 10.1097/00007632-199601150 00014
  46. Ahn S.H., Park H.W., Byun W.M., et al. Comparison of clinical outcomes and natural morphologic changes between sequestered and large central extruded disc herniations. Yonsei Med J. 2002;43(3):283-90. doi: 10.3349/ymj.2002.43.3.283.
  47. Sherman J., Cauthen J., Schoenberg D., et al. Economic impact of improving outcomes of lumbar discectomy. Spine J. 2010;10(2):108-116. doi: 10.1016/j.spinee.2009.08.453.
  48. Крылов В.В., Коновалов А.Н., Дашьян В.Г и др. состояние нейрохирургии в Российской Федерации. Нейрохирургия. 2016;(3):3-44. Ktylov V.V., KonovalovA.N., Dash'Yan V.G., et al. The current state of neurosurgery in Russian Federation. Neirokhirurgiya=Russian journal of neurosurgery. 2016;(3):3-44. (In Russ.)].
  49. Davis R.A. A long-term outcome analysis of 984- surgically treated her lumbar discs. J Neurosurg. 1994;80:415-421. doi: 10.3171/ jns.1994.80.3.0415.
  50. Ml. McCulloch J.A., Young PH. Essentials of spinal microsurgery. Philadelphia, 1998.
  51. Papadakis M., Aggeliki L., Papadopoulos E.C., Girardi F.P Common surgical complications in degenerative spinal surgery World J Orthop. 2013;4(2):62-66. doi: 10.5312/wjo.v4.i2.62.
  52. Aizawa T, Ozawa H., Kuusakabe T., et al. Reoperation for recurrent lumbar disc herniation: a study over a 20-year period in a Japa nese population. J. Orthop Sci. 2012;17(2):107-113. doi: 10.1007/s00776-011-0184-6
  53. An H.S., Silveri C.P, Simpson J.M., et al. Comparison of smoking habits between patients with surgically confirmed herniated lumbar and cervical disc disease and controls. J Spinal Disord. 1994;7:369-373.
  54. Wang Y, Dai G., Jiang L., Liao S. The incidence of regression after the non-surgical treatment of symptomatic lumbar disc herniation: a systematic review and meta-analysis BMC Musculoskelet Disord. 2020;21:530. doi: 10.1186/s12891-020-03548-z.
  55. Fountas K.N., Kapsalaki E.Z., Nikolakakos L.G., et al. Anterior cervical discectomy and fusion associated complications. Spine. 2007;32(21): 2310-7. doi: 10.1097/BRS.0b013e318154c57e.
  56. Macki M., Hernandez-Hermann M., Bydon M., et al. Spontaneous regression of sequestrated lumbar disc herniations: literature review. Clin Neurol Neurosurg. 2014;120:136-41. doi: 10.1016/j. clineuro.2014.02.013.
  57. Chiu C.C., Chuang TY, Chang K.H., et al. The probability of spontaneous regression of lumbar herniated disc: a systematic review. Clin Rehabil. 2015;29(2):184-95. doi: 10.1177/0269215514540919.
  58. Жезлов М.М., Левин О.С. Диагностика и лечение вертеброгенной пояснично-крестцовой радику-лопатии. Современная терапия в психиатрии и неврологии. 2012;4:31-36.
  59. Elkan P, Sten-Linder M., Hedlund R., et al. Markers of inflammation and fibrinolysis in relation to outcome after surgery for lumbar disc herniation. A prospective study on 177 patients. Eur Spine J. 2016;25(1):186 91. doi: 10.1007/s00586-015-3998-7

Қосымша файлдар

Қосымша файлдар
Әрекет
1. JATS XML

Осы сайт cookie-файлдарды пайдаланады

Біздің сайтты пайдалануды жалғастыра отырып, сіз сайттың дұрыс жұмыс істеуін қамтамасыз ететін cookie файлдарын өңдеуге келісім бересіз.< / br>< / br>cookie файлдары туралы< / a>