Scientific rationale and prerequisites for the use of direct oral anticoagulants for the prevention of thromboembolic complications in patients with COVID-19
- Authors: Otdelenov V.A1, Matveev A.V1, Mirzaev K.B1, Sychev D.A1
-
Affiliations:
- Russian Medical Academy of Continuous Professional Education
- Issue: Vol 27, No 14 (2020)
- Pages: 10-15
- Section: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/313004
- DOI: https://doi.org/10.18565/pharmateca.2020.14.10-15
- ID: 313004
Cite item
Abstract
The review presents an analysis of data on the use of direct oral anticoagulants for the prevention of thrombotic complications in patients with COVID-19, according to the results of published clinical studies, national guidelines for the management of patients with new coro-navirus infection, protocols of university hospitals, and clinical trials.
Full Text
About the authors
V. A Otdelenov
Russian Medical Academy of Continuous Professional EducationMoscow, Russia
A. V Matveev
Russian Medical Academy of Continuous Professional EducationMoscow, Russia
K. B Mirzaev
Russian Medical Academy of Continuous Professional EducationMoscow, Russia
D. A Sychev
Russian Medical Academy of Continuous Professional EducationMoscow, Russia
References
- Deng Y., Liu W., Liu K., et al. Clinical characteristics of fatal and recovered cases of coronavirus disease 2019 in Wuhan, China: a retrospective study. Chin MedJ (Engl). 2020;133(11):1261-57. doi: 10.1097/CM9.0000000000000824.
- Li T, Lu H, Zhang W. Clinical observation and management of COVID-19 patients. Emerg. Microb Infect. 2020;9(1):687-90. doi: 10.1080/22221751.2020.1741327.
- Thachil J., Tang N., Gando S., et al. ISTH interim guidance on recognition and management of coagulopathy in COVID-19. J ThrombHaemost. 2020;18(5):1023-26. doi: 10.1111/jth.14810.
- American Society of Hematology. COVID-19 and coagulopathy: frequently asked questions. From the ASH website. (Version 4.0; last updated September 24, 2020) [Internet]. [cited 2020 Nov 14]. Available from: https://www.hematology. org/covid-19/covid-19-and-coagulopathy.
- Tang N, Li D., Wang X., Sun Z. Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia. J. Thromb Haemost. 2020;18(4):844-47. doi: 10.1111/jth.14768.
- Guan W., Ni Z., Hu Y., et al. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 2020;382(18):1708-20. Doi: 10.1056/ NEJMoa2002032.
- Wu C, Chen X., Cai Y., et al. Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China. JAMA. Intern. Med. 2020;180(7):934. Doi: 10.1001/ jamainternmed.2020.0994.
- Kunutsor S.K., Laukkanen J.A. Incidence of venous and arterial thromboembolic complications in COVID-19: A systematic review and metaanalysis. Thromb Res. 2020;196:27-30. doi: 10.1016/j.thromres.2020.08.022.
- Yale School Of Medicine. COVID-19 Treatment Algorithm. Updated 10/27/20 COVID-19 TREATMENT ADULT_10.27.2020_ 398806_5_v1.pdf.
- Временные методические рекомендации Министерства здравоохранения РФ по профилактике, диагностике и лечению новой коронавирусной инфекции (COVID-19), версия 9 от 26.10.2020 [Internet]. Cited 2020 Nov 15.
- Mount Sinai COVID-19 Anticoagulation Algorithm. Version 1.1 (April 9, 2020) [Internet]. [cited 2020 Nov 15]. Available from: https:// emergencymedicinecases.com/wp-content/ uploads/2020/04/COVID-19-Anticoagulation- Algorithm-version_final_1.1.pdf?
- Рекомендации МГНОТ по диагностике и интенсивной терапии синдрома диссеминированного внутрисосудистого свертывания крови при вирусном поражении легких. Под ред. П.А. Воробьева, В.А. Елыкомова. Проблемы стандартизации в здравоохранении 2020. C. 5-6. doi: 10.26347/1607-2502202005-06099-111.
- NIH COVID-19 Treatment Guidelines [Internet]. [cited 2020 Nov 15]. Available from: https:// www.covid19treatmentguidelines.nih.gov.
- UW Medicine COVID-19 Resource Site [Internet]. University of Washington. 2020. Available from: https://covid-19.uwmedicine.org/Pages/ default.aspx.
- Bikdeli B., Madhavan M.V., Jimenez D., et al. COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-Up. J Am Coll Cardiol. 2020;75(23):2950-73. Doi: 10.1016/ jjacc.2020.04.031.
- Brigham and Women's Hospital COVID-19 Protocols [Internet]. 2020. Available from: https:// covidprotocols.org.
- Massachusetts General Hospital (MGH) COVID-19 Treatment Guidance [Internet]. 2020 [cited 2020 Jun 26]. Available from: https://www. massgeneral.org/assets/MGH/pdf/news/coronavirus/mass-general-COVID-19-treatment-guidance.pdf.
- McBane R.D., Torres Roldan V.D., Niven A.S., et al. Anticoagulation in COVID-19: A Systematic Review, Meta-analysis, and Rapid Guidance From Mayo Clinic. Mayo Clin Proc. 2020;95(11):2467-86. doi: 10.1016/j.mayocp.2020.08.030.
- Marietta M., Ageno W., Artoni A., et al. COVID-19 and haemostasis: A position paper from Italian Society on Thrombosis and Haemostasis (SISET). Blood Transfus. 2020;18(3):167-69. doi: 10.2450/2020.0083-20.
- Рекомендации по диагностике и интенсивной терапии синдрома диссеминированного внутрисосудистого свертывания крови при вирусном поражении легких. doi: 10.26347/1607-2502202005-06099- 111.
- Search of: DOAC OR rivaroxaban OR apixa-ban OR dabigatran COVID-19 - List Results -ClinicalTrials.gov [Internet]. [cited 2020 Nov 15]. Available from: https://clinicaltrials.gov/ct2/ results?cond=COVID-19&term=DOAC+OR+riva roxaban+OR+apixaban+OR+dabigatran&cntry= &state=&city=&dist.
- Iturbe-Hernandez T., Garcia de Guadiana Romualdo L., Gil Ortega I., et al. Dabigatran, the oral anticoagulant of choice at discharge in patients with non-valvular atrial fibrillation and COVID-19 infection: the ANIBAL* protocol. Drugs Context. 2020;9:1-12. Doi: 10.7573/ dic.2020-8-3.
- Angus D.C., Berry S., Lewis R.J., et al. The REMAP-CAP (Randomized Embedded Multifactorial Adaptive Platform for Community-acquired Pneumonia) Study. Rationale and Design. Ann Am Thorac Soc. 2020;17(7):879-91. Doi: 10.1513/ AnnalsATS.202003-192SD.
- Sivaloganathan H., Ladikou E.E., Chevassut T. COVID-19 mortality in patients on anticoagulants and antiplatelet agents. Br J Haematol. 2020;190(4).doi: 10.1111/bjh.16968.
- Cohen A.T., Spiro T.E., Buller H.R., et al. Rivaroxaban for Thromboprophylaxis in Acutely Ill Medical Patients. N Engl J Med. 2013;368(6):513-23. doi: 10.1056/NEJMoa1111096.
- Goldhaber S.Z., Leizorovicz A., Kakkar A.K., et al. Apixaban versus Enoxaparin for Thromboprophylaxis in Medically Ill Patients. N Engl J Med. 2011;365(23):2167-77. doi: 10.1056/NEJMoa1110899.
- Flam B., Wintzell V., Ludvigsson J.F., et al. Direct oral anticoagulant use and risk of severe COVID-19. J Intern Med. 2020;joim.13205. doi: 10.1111/joim.13205.
- Testa S., Prandoni P., Paoletti O., et al. Direct oral anticoagulant plasma levels' striking increase in severe COVID-19 respiratory syndrome patients treated with antiviral agents: The Cremona experience. J Thromb Haemost. 2020;18(6):1320-23. doi: 10.1111/jth.14871.
- Detailed recommendations for interactions with experimental COVID-19 antiviral therapies. Updated 24 September 2020. University of Liverpool [Internet]. Available from: https:// www.covid19-druginteractions.org/prescribing-resources.