PREDOPERATsIONNAYa KhIMIOTERAPIYa PRI REZEKTABEL'NYKh METASTAZAKh KOLOREKTAL'NOGO RAKA V PEChENI


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Abstract

Colorectal cancer (CR) is a leader in the morbidity and mortality from malignant tumors. Currently, along with chemotherapy, liver resection remains the only method allowing to achieve recovery in patients with colorectal liver metastases. Preoperative chemotherapy improves radicality of operation by reduction of metastases size and eradication of micrometastases. Moreover, the assessment of the drug-induced pathomorphism provides more reasonable choice of postoperative management. Several studies have shown an advantage of perioperative chemotherapy in resectable colorectal liver metastases. The role of preoperative chemotherapy, however, is not well-understood and requires further research.

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E. V Chernoglazova

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