Osteoporosis in real clinical practice: focus on alfacalcidol


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Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Рұқсат ақылы немесе тек жазылушылар үшін

Аннотация

The article presents the results of survey of physicians of 6 specialties involved in the treatment of osteoporosis, and patients suffering from this disease. A survey of doctors has showed that they appoint alfacalcidol to 27% of patients, including as a monotherapy in 8% of cases. Among patients, 25% of the respondents received alfacalcidol in combination with other drugs for the treatment of osteoporosis (22%), or as monotherapy (3%). In addition, article presents the analysis of the literature, which is justified the advantages of alfacalcidol from the perspective of evidence-based medicine.

Негізгі сөздер

Толық мәтін

Рұқсат жабық

Авторлар туралы

N. Toroptsova

FSBIS “Scientific Research Institute of Rheumatology n.a.V.A. Nasonova"

Email: torop@irramn.ru
Laboratory of Osteoporosis

O. Nikitinskaya

FSBIS “Scientific Research Institute of Rheumatology n.a.V.A. Nasonova"

MD, Head of Laboratory of Osteoporosis

Әдебиет тізімі

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  2. Mehsen N., Paccou J., Confavreux C.B., David C., Leboime A., Laroche M. Management of patients with incident fractures during osteoporosis treatment. Joint Bone Spine. 2010;77(2):133-38.
  3. Nuti R., Bianchi G., Brandi M.L., Caudarella R., D'Erasmo E., Fiore C., Isaia G.C., Luisetto G., Muratore M., Oriente P., Ortolani S. Superiority of alfacalcidol compared to vitamin D plus calcium in lumbar bone mineral density in postmenopausal osteoporosis. Rheumatol. Int. 2006;26(5):445-53.
  4. Ringe J.D., Farahmand P., Schacht E. Alfacalcidol in men with osteoporosis: a prospective, observational, 2-year trial on 214 patients. Rheumatol. Int. 2013;33(3):637-43.
  5. Ringe J.D., Dorst A., Faber H., Schacht E., Rahlfs V.W. Superiority of alfacalcidol over plain vitamin D in the treatment of glucocorticoid-induced osteoporosis. Rheumatol. Int. 2004;24(2):63-70.
  6. Ringe J.D., Faber H., Fahramand P., Schacht E. Alfacalcidol versus plain vitamin D in the treatment of glucocorticoid/inflammation-induced osteoporosis. J. Rheumatol. 2005;76(Suppl.):33-40.
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  13. Ito S., Harada A., Kasai T., Sakai Y., Takemura M., Matsui Y., Hida T., Ishiguro N. Use of alfacalcidol in osteoporotic patients with low muscle mass might increase muscle mass: an investigation using a patient database. Geriatr. Gerontol. Int. 2014;14(Suppl 1):122-28.
  14. Scharla S.H., Schacht E., Bawey S., Kamilli I., Holle D., Lempert U.G. Pleiotropic effect of alfacalcidol in elderly patients with rheumatoid arthritis. Arthr. Rheum. 2003;23:268-74.
  15. Ringe J.D., Schacht E. Naturliches Vitamin D oder Alfacalcidol als Folgebehandlung langjahriger Bisphosphonat-Therapie bei postmenopausaler Osteoporose. Osteology. 2012;21:83-7.
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