LUPUS NEPHRITIS: MODERN THERAPY


Cite item

Full Text

Abstract

The article discusses approaches to the treatment of lupus nephritis on the basis of its severity. Therapeutic indications for the administration of certain immunosuppressive drugs, including mycophenolat mofetil, are especially presented.

References

  1. Korbet S.M. , Lewis E.J., Schwartz M.M. et al. Factors predictive of outcome in severe lupus nephritis. Lupus Nephritis Collaborative Study Group. Am. J. Kidney Dis. 2000; 35(5): 904-914
  2. Illei G.G., Austin H.H., Crane M. et al. Combination therapy with pulse cyclophosphamide plus pulse methylprednisolone improves long-term renal outcome without adding toxicity in patients with lupus nephritis. Ann. Int. Med. 2001; 135(4): 248-257
  3. Houssiau F.A., Vasconselos C., D'Cruz D. et al. Immunosuppressive therapy in lupus nephritis: the Euro-Lupus Nephritis Trial, a randomized trial of low-dose versus high-dose intravenous cyclophosphamide. Arthritis Rheum. 2002; 46(8): 2121-2131
  4. D'Cruz D.P., Houssiau F.A. The Euro-Lupus Nephritis Trial: the development of the sequential treatment protocol. Lupus 2009; 18(10): 875-877
  5. Chan T.M., Li F.K., Tang C.S. et al. Efficacy of mycophenolate mofetil in patients with diffuse proliferative lupus nephritis. Hong Kong-Guangzhou Nephrology Study Group. N. Engl. J. Med. 2000; 343(16): 1156-1162
  6. Chan T.M., Tse K.C., Tang C.S. et al. Long-term study of mycophenolate mofetil as continuous induction and maintenance treatment for diffuse proliferative lupus nephritis. J. Am. Soc. Nephro. 2005; 16(4): 1076-1084
  7. Ong L.M., Hooi L.S., Lim T.O. et al. Randomized controlled trial of pulse intravenous cyclophosphamide versus mycophenolate mofetil in the induction therapy of proliferative lupus nephritis. Nephrology (Carlton). 2005; 10(5): 504-510
  8. Ginzler E.M., Dooley M.A., Aranow C. et al. Mycophenolate mofetil or intravenous cyclophosphamide for lupus nephritis. N. Engl. J. Med. 2005; 353(21): 2219-2228
  9. Moore R.A., Derry S. Systematic review and meta-analysis of randomised trials and cohort studies of mycophenolate mofetil in lupus nephritis. Arthritis Res. Ther. 2006; 8(6): R182
  10. Walsh M., James M., <http://www.ncbi.nlm.nih.gov/pubmed?term=%22Jayne%20D%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstract>et al. Mycophenolate mofetil for induction therapy of lupus nephritis: a systematic review and meta-analysis. Clin. J. Am. Soc. Nephrol. 2007; 2(5): 968-975
  11. Zhu B., Chen N., Lin Y. et al. Mycophenolate mofetil in induction and maintenance therapy of severe lupus nephritis: a meta-analysis of randomized controlled trials. Nephrol. Dial. Transplant. 2007; 22(7): 1933-1942
  12. Appel G.B., Contreras G., Dooley M.A. et al.; Aspreva Lupus Management Study Group. Mycophenolate mofetil versus cyclophosphamide for induction treatment of lupus nephritis. J. Am. Soc. Nephrol. 2009; 20(5): 1103-1112
  13. Contreras G., Pardo V., Leclercq B. et al. Sequential therapies for proliferative lupus nephritis. N. Engl. J. Med. 2004; 350(10): 971-980.

Supplementary files

Supplementary Files
Action
1. JATS XML

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies