Open Access
Access granted
Subscription or Fee Access
No 1 (2010)
- Year: 2010
- Articles: 16
- URL: https://journals.eco-vector.com/2075-3594/issue/view/6292
Articles
4-10
11-15
16-26
21-26
27-30
31-35
36-40
EFFECT OF RENAL ANEMIA ON RENAL FUNCTION AND SURVIVAL OF PATIENTS WITH CHRONIC GLOMERULONEPHRITIS
Abstract
Purpose. The evaluation of effect of anemia on the dynamics of renal function in patients with chronic glomerulonephritis (CGN).
Materials and methods. The study enrolled 54 patients with CGN (15 CGN patients with anemia and 39 patients with CGN without anemia). According to the presence of anemia, they were divided into 2 groups, matched by sex and age. Comparisons of conventional clinical and laboratory parameters, including characterizing the renal function, were performed. Survival rate was assessed by the Kaplan-Meier method using the log-rank test (Log Rank). Statistical validity of data differences was evaluated by the Student t-test.
Results. The presence of anemia in patients with CGN is associated with the increased creatinemia, proteinuria, high serum triglyceride and LDL levels, and low glomerular filtration rate. Anemia causes a significant decrease in 5-year and 10-year survival in patients with CGN.
Conclusion. Anemia in patients with CGN is associated with greater severity of renal insufficiency, metabolic disorders, as well as reduced 5 - and 10-year survival
Clinical nephrology. 2010;(1):41-43
41-43
CARDIORENAL CONTINUUM OR CARDIORENAL SYNDROME?
Abstract
Purpose. Characterization of patients with chronic heart failure (CHF) associated with chronic kidney disease (CKD).
Materials and methods. Study enrolled 368 patients (187 men, 181 women) with II-IV FC CHF aged 18 - 84 years (mean age, 60 ± 10 years). The majority of patients - 247 (67%) had CHF with preserved ejection fraction. Glomerular filtration rate was calculated by MDRD formula, CKD diagnosed according to the NKF K/ DOQI, Guidelines, 2002.
Results. GFR was 68.8 ± 20.9 ml/min/1.73m2 (18.4 to 142.6 ml/min/1,73m2), whereas GFR <60 ml/min/1.73 m2 was observed in 136 (37%) patients. CHF preceded decrease in renal function in 72 (53%) patients; in 27 (20%) patients it was impossible to determine what came first - heart failure or renal dysfunction; in 7 (5%) patients renal dysfunction preceded the appearance of CHF. 42 patients had diabetes mellitus, therefore it was impossible to determine the causal relationship between heart failure and renal dysfunction.
Conclusion. Renal impairment occurs in one third of patients with CHF. In many cases, it is impossible to determine cause-effect relationship between the pathology of heart and kidney. The authors proposed own variant of classification, which in addition to acute and chronic cardiorenal syndrome and renokardial syndrome determine types of these syndromes: type 1 - the cause-effect relationships between the dysfunction of the heart and kidneys are defined, type 2 - it is unknown tat was the cause, and that a result.
Clinical nephrology. 2010;(1):44-48
44-48
ESSENTIAL ARTERIAL HYPERTENSION AND CHRONIC RENAL FAILURE IN PATIENTS WITH LONG-TERM FOLLOW-UP IN MULTIDISCIPLINARY OUTPATIENT HEALTH CARE FACILITY
Abstract
Purpose. Evaluation of the prevalence and prognostic significance of essential arterial hypertension (EAH) in patients with chronic renal failure with long-term follow-up in a large multidisciplinary outpatient medical facility.
Materials and methods. The medical records of 175 patients (144 men and 31 women) aged 32 to 95 years (mean age, 78.6 years) with chronic renal insufficiency (glomerular filtration rate (GFR) <50 ml/min) were retrospectively analyzed. Maximum duration of follow-up was 30 years. Biochemical blood parameters, including creatinemia, and changes in urine were examined. Imaging survey methods were used as appropriate. Etiology of CRF was especially defined in all patients.
Results. The presence of EAH with different degrees of reduction of glomerular filtration rate was associated with a significant increase in the frequency of complicated forms of coronary artery disease, atrial fibrillation, as well as diabetic nephropathy, urate nephropathy, and ischemic kidney disease.
Conclusion. EAH is assosiated with increased risk of cardiovascular complications in patients with chronic renal failure that determines the need for optimizing antihypertensive therapy on an outpatient phase.
Clinical nephrology. 2010;(1):49-52
49-52
53-56
DIAGNOSIS AND TREATMENT OF VENOUS RENAL HYPERTENSION IN CHILDREN AND ADOLESCENTS
Abstract
Renal vein outflow obstruction of different origin is accompanied by renal venous hypertension. Renal venous hypertension is accompanied by anasthomosis development and, in some cases, lead to chronic kidney disease. In this article ethiology, pathogenesis, diagnosis and treatment of renal venous hypertension are discussed
Clinical nephrology. 2010;(1):57-59
57-59
60-64
65-69
70-71
72-73