EFFECT OF RENAL ANEMIA ON RENAL FUNCTION AND SURVIVAL OF PATIENTS WITH CHRONIC GLOMERULONEPHRITIS
- Authors: Kaliev RR1, Budaychieva AB1, Murkamilov IT1, Kaliev R1, Budaichieva A1, Murkamilov I1
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Affiliations:
- Issue: No 1 (2010)
- Pages: 41-43
- Section: Articles
- URL: https://journals.eco-vector.com/2075-3594/article/view/245846
- ID: 245846
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Abstract
Purpose. The evaluation of effect of anemia on the dynamics of renal function in patients with chronic glomerulonephritis (CGN).
Materials and methods. The study enrolled 54 patients with CGN (15 CGN patients with anemia and 39 patients with CGN without anemia). According to the presence of anemia, they were divided into 2 groups, matched by sex and age. Comparisons of conventional clinical and laboratory parameters, including characterizing the renal function, were performed. Survival rate was assessed by the Kaplan-Meier method using the log-rank test (Log Rank). Statistical validity of data differences was evaluated by the Student t-test.
Results. The presence of anemia in patients with CGN is associated with the increased creatinemia, proteinuria, high serum triglyceride and LDL levels, and low glomerular filtration rate. Anemia causes a significant decrease in 5-year and 10-year survival in patients with CGN.
Conclusion. Anemia in patients with CGN is associated with greater severity of renal insufficiency, metabolic disorders, as well as reduced 5 - and 10-year survival
Materials and methods. The study enrolled 54 patients with CGN (15 CGN patients with anemia and 39 patients with CGN without anemia). According to the presence of anemia, they were divided into 2 groups, matched by sex and age. Comparisons of conventional clinical and laboratory parameters, including characterizing the renal function, were performed. Survival rate was assessed by the Kaplan-Meier method using the log-rank test (Log Rank). Statistical validity of data differences was evaluated by the Student t-test.
Results. The presence of anemia in patients with CGN is associated with the increased creatinemia, proteinuria, high serum triglyceride and LDL levels, and low glomerular filtration rate. Anemia causes a significant decrease in 5-year and 10-year survival in patients with CGN.
Conclusion. Anemia in patients with CGN is associated with greater severity of renal insufficiency, metabolic disorders, as well as reduced 5 - and 10-year survival
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