The pathomorphological changes in the kidneys of rats in the experimental simulations of infection and non-infected vesicoureteric reflux (experimental study)


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Abstract

Path morphological changes in the kidneys of rats were studied in the experimental simulations of urethral stenosis, urinary tract infection, as well as their combination. It is ascertained that every time the simulated pathological processes are be observed, the considerable morphological changes mainly occurred in the tubules and interstitial of the kidneys. The changes presented with signs of infiltrative-productive inflammation as well as fibrosis of differing levels of intensity. A definite correlation between the type of simulated pathological process and the intensity of morphological changes in the kidneys was revealed.

References

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