Acute kidney injury in coronary heart disease after revascularization procedure: risk factors and outcomes

Aim. Analysis of risk factors and outcomes of acute kidney injury (AKIN) in coronary heart disease (CHD) patients, undergone coronary revascularization. Methods. 56 CHD patients, undergone coronary revascularization, were included into the study. Patients were divided into 2 groups: 1st (n=28, mean age 69,0±i,7 years, male/female (M/F) = 1/1) - with akin after coronary revascularization; 2nd (N = 28, MEAN AGE 56,8±1,7 years, male/female (M/F) = 6/1) - without akin. 30 healthy volunteers (mean age 49,З±З,5 years, M/F=3/1) were included into the control group. Anamnesis, clinical and laboratory parameters were analysed; estimeted glomerular filtration rate (eGFR) was assessed by Cockroft-Gault formula; ultrasound Doppler scaning of kidneys was performed. Results. Main risk factor for AKIN after coronary revascularization was baseline eGFR <60 ml/min/1,73m 2. Combination of risk factors increased risk of AKIN after coronary revascularization. Mortality of patients with AKIN after coronary revascularization was 25%. Conclusion. Risk of acute kidney injury after coronary revascularization increases in patients with baseline estimated glomerular filtration rate <60 ml/min/1,73m 2.

ischemic kidney disease, coronary revascularization, acute kidney injury, risk factors