The relationship of bendopnea and change in renal filtration function in patients with chronic heart failure


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Abstract

Objective. evaluation of the relationship between bendopnea and changes in the renal filtration function in patients with chronic heart failure (CHF). material and methods. the study included 104 patients with heart failure from the register "Management of chronic patients with multiple diseases"; the mean age of patients was 72.8±10.6 years. all patients underwent a test to determine the presence of a bendopnea symptom, calculating glomerular filtration rate (GFR) at baseline and after 2 years of follow-up. Two groups of patients were formed: group 1-67 (64.42%) patients with a positive bendopnea test, group 2-37 (35.58%) - with a negative bendopnea test. results. in the cohort studied, mean gfr was 59.2±16.9 ml/min/1.73 m2. at the inclusion visit, the prevalence of chronic kidney disease (ckd) did not significantly differ between groups. after two years of follow-up, 12 patients with ckd progression were identified in group 1, while in group 2 there were only three such patients. the construction of a logistic model made it possible to determine the significant effect of the presence of a bendopnea symptom on the ckd dynamics: the risk of an increase in the ckd stage increased by 1.29 times (P

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About the authors

Dmitry O. Dragunov

Pirogov Russian National Research Medical University; Research Institute of Healthcare Organization and Medical Management of the Moscow Healthcare Department

Email: tamops2211@gmail.com
PhD in Medical Sciences, Associate Professor at the Department of Propaedeutics of Internal Diseases, Faculty of Pediatrics; Head of Organizational and Methodological Department for the Treatment Moscow, Russia

Anna V. Sokolova

Pirogov Russian National Research Medical University; Research Institute of Healthcare Organization and Medical Management of the Moscow Healthcare Department

PhD in Medical Sciences, Associate Professor at the Department of Propaedeutics of Internal Diseases Faculty of Pediatrics; Leading Specialist at the Organizational and Methodological Department for the Treatment Moscow, Russia

A. D Gasanova

Pirogov Russian National Research Medical University; Research Institute of Healthcare Organization and Medical Management of the Moscow Healthcare Department

Teaching Assistant at the Department of Propaedeutics of Internal Diseases Faculty of Pediatrics; Specialist at the Organizational and Methodological Department for the Treatment Moscow, Russia

Grigory P. Arutyunov

Pirogov Russian National Research Medical University

Doctor of Medical Sciences, Professor, Corresponding Member of RAS, Head of the Department of Propaedeutics of Internal Diseases Faculty of Pediatrics Moscow, Russia

References

  1. Hill N.R., Fatoba S.T., Oke J.L., et al. Global Prevalence of Chronic Kidney Disease - A Systematic Review and Meta-Analysis. PLoS One. 2016;11(7):e0158765.
  2. Saritas T., Floege J. Cardiovascular disease in patients with chronic kidney disease. Herz. 2020 Jan. 14;1-7.
  3. Thibodeau J.T., Turer A.T., Gualano S.K., et al. Characterization of a novel symptom of advanced heart failure: bendopnea. JACC. Heart Failure. 2014;2(1):24-31.
  4. Арутюнов Т.П., Драгунов Д.О., Соколова А.В., Митрохин В.М. и др. Факторы, ассоциированные с уровнем интерлейкинов-18, -8 и -6у пациентов с гипертонической болезнью высокого и очень высокого сердечнососудистого риска. Кардиология. 2017;57(3):69-75.
  5. Драгунов Д.О., Соколова А.В., Арутюнов Т.П., Митрохин В.М. и др. Взаимосвязь уровня ИЛ-18, ИЛ-6 и уровня потребления натрия у пациентов с гипертонической болезнью и сахарным диабетом. Кардиология. 2017;57(1):355-359.
  6. Dick S.A., Epelman S. Chronic Heart Failure and Inflammation: What Do We Really Know? Circ. Res. 2016;119(1):159-176.
  7. Matsushita K, van der Velde M., Astor B., et al. Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality: a collaborative meta-analysis of general population cohorts Lancet. 2010;375(9731):2073-2081.
  8. Van Biesen W., De Bacquer D., Verbeke F., et al. The glomerular filtration rate in an apparently healthy population and its relation with cardiovascular mortality during 10years. Eur. Heart J. 2007;28(4):478-483.
  9. Арутюнов Т.П., Драгунов Д.О., Соколова А.В. Влияние петлевых диуретиков с различным периодом полувыведения на динамику натрий-уреза и показатели, характеризующие состояние тубулоинтерсти-циальной ткани почек. Тер. архив. 2014;86(6):38-44.
  10. Arutyunov G.P., Dragunov D.O., Sokolova A.V. The effect ofloop diuretics with different half-lives on the dynamics of sodium nitridesis and indicators characterizing the state of tubulointerstitial tissue of the kidneys. Ter. arkhiv. 2014;86(6):38-44. (In Russ.)].
  11. Смирнов А.В., Шилов Е.М., Добронравов В.А. Национальные рекомендации. Хроническая болезнь почек: основные принципы скрининга, диагностики, профилактики и подходы к лечению. Клин. нефрология. 2012;4:4-
  12. Ponikowski P.A., Voors A.D., Anker S., et al. 2016 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure. Rus. J. Cardiol. 2017;22 (1):7-81.
  13. Драгунов Д.О., Соколова А.В., Арутюнов Т.П. и др. Выраженность бендопноэ как прогностический маркер декомпенсации хронической сердечной недостаточности. Клин. фармакология и терапия. 2018;27(5):52-56.
  14. Ronco C., Haapio M., House A.A., et al. Cardiorenal syndrome. J. Am. Coll. Cardiol 2008;52(19):1527-1539.
  15. Сторожаков Т.И., Тендлин Т.Е., Резник Е.В. Поражение почек у больных с хронической сердечной недостаточностью. Основные направления в лечении больных с хронической сердечной недостаточностью: Руководство для врачей-терапевтов, врачей общей практики. Под ред. Т.И. Сторожакова, Т.Е. Гендлина. М., 2008. С. 137-149.
  16. Арутюнов Т.П. Патофизиологические процессы в почках у больных ХСН. Сердечная недостаточность. 2008;9(5):234-249
  17. Tabrizi R., Zolala F., Nasirian M., et al. Estimation of the prevalence of chronic kidney disease: The results of a model based estimation in Kerman, Iran. Med. J. Islam. Repub. Iran. 2016;5(30):338.
  18. Пигарева Ю.А., Авдошина С.В., Дмитрова Т.Б. и др. Распространенность хронической болезни почек среди пациентов терапевтического стационара. Клин. нефрология. 2012;3:4-9. [Pigareva YU.A., Avdoshina S.V., Dmitrova T.B. i dr. Prevalence of chronic kidney disease among patients in a therapeutic hospital. Klin. nefrologiya. 2012;3:4-9. (In Russ.)].
  19. Драгунов Д.О., Соколова А.В., Латышев Т.В., Арутюнов Т.П. Распространенность хронической болезни почек у коморбидных пациентов. Клин. нефрология. 2016;3-4:49-52. [Dragunov D.O., Sokolova A.V., Latyshev T.V., Arutyunov G.P. The prevalence of chronic kidney disease in comorbidpatients. Klin. nefrologiya. 2016;3-4:49-52. (In Russ.)].
  20. Tuegel C., Bansal N. Heart failure in patients with kidney disease. Heart. 2017;103(23):1848-1853.
  21. Schefold J.C., Filippatos G., Hasenfuss G., et al. Heart failure and kidney dysfunction: epidemiology, mechanisms and management. Nat. Rev. Nephrol. 2016;12(10):610-623.

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