Squamous cell cancer in renal transplant recipients: a real threat?

Immunosuppressive therapy after solid organ transplantation significantly increases the risk of developing cancer compared with the general population. we present our own observation of a severe course of metastatic squamous cell skin cancer in a patient with satisfactory graft function io years after cadaveric kidney transplantation, who standard 3-component immunosuppression. despite surgical treatment and a course of radiation, the disease was accompanied by rapid progression and death. Long-term immunosuppressive therapy after kidney transplantation significantly increases the likelihood of developing malignant skin tumors. however, the risk increases significantly over time. therefore, dermatological examinations should be included in the management protocol for renal transplant recipients in order to detect the disease earlier, with particular attention to patients with more than ten years of immunosuppression. if squamous cell skin cancer is confirmed, continued immunosuppressive therapy is associated with a high risk of progression and fatal outcome of the disease.

kidney transplantation, skin neoplasms, squamous cell carcinoma, immunosuppression