Squamous cell cancer in renal transplant recipients: a real threat?


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Resumo

Immunosuppressive therapy after solid organ transplantation significantly increases the risk of developing cancer compared with the general population. we present our own observation of a severe course of metastatic squamous cell skin cancer in a patient with satisfactory graft function io years after cadaveric kidney transplantation, who standard 3-component immunosuppression. despite surgical treatment and a course of radiation, the disease was accompanied by rapid progression and death. Long-term immunosuppressive therapy after kidney transplantation significantly increases the likelihood of developing malignant skin tumors. however, the risk increases significantly over time. therefore, dermatological examinations should be included in the management protocol for renal transplant recipients in order to detect the disease earlier, with particular attention to patients with more than ten years of immunosuppression. if squamous cell skin cancer is confirmed, continued immunosuppressive therapy is associated with a high risk of progression and fatal outcome of the disease.

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Sobre autores

Dmitry Perlin

Volgograd Regional Uronephrological Center

Email: dvperlin@mail.ru
Dr.Sci. (Med.), Professor, Chief Physician Volgograd Region, Volzhsky, Russia

Ivan Dymkov

Volgograd Regional Uronephrological Center

Cand. Sci. (Med.), Deputy Chief Physician Volgograd Region, Volzhsky, Russia

Shamil Shamkhalov

Volgograd Regional Uronephrological Center

Urologist, Department of Urology Volgograd Region, Volzhsky, Russia

Anastasia Perlina

M.F. Vladimirsky Moscow Regional Research and Clinical Institute

Dermatovenereologist, Department of Telemedicine Technologies Moscow, Russia

Pavel Kulikov

Volgograd Regional Uronephrological Center

Urologist, Department of Urology Volgograd Region, Volzhsky, Russia

Bibliografia

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