Clinical and morphological charasteristics of focal-segmental glomerulosclerosis in Kazakh children


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Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Рұқсат ақылы немесе тек жазылушылар үшін

Аннотация

Aim. Characteristics of clinical and morphological signs of focal segmental glomerulosclerosis in Kazakh children. Methods. Focal segmental glomerulosclerosis (FSGS) was diagnosed in renal biopsy in 19 children with steroid-resistant nephrotic syndrome. Clinical, laboratory signs and renal prognosis were analyzed. Results. In 47,4% of children tip-lesion or typical variants of FSGS were found. Cellular and perihilar variants of FSGS were not found. There were significant correlations between glomerular and tubular damage. Arterial hypertension and hematuria, but not proteinuria, determinate poor prognosis in FSGS. Conclusion. One of the main causes of steroid-resistant nephrotic syndrome in Kazakh children is typical or tiplesion variants of focal segmental glomerulosclerosis.

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Әдебиет тізімі

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