Role of sulodexide in treatment of diabetic nephropathy in patients with type 1 diabetes mellitus

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Resumo

Aim. Determination of efficacy of sulodexide in diabetes mellitus (DM) type 1 patients with diabetic nephropathy (DN).
Methods. 108 patients (19 male, 17 female, age 24-27 years, mean duration of DM 7 - 16 years) were included into the study. 62 patients at baseline had microalbuminuria, 46 - proteinuria. The duration of treatment course with sulodexide was 4 weeks.
Results. Patients with microalbuminuria demonstrated significant decrease of albuminuria, in 50% of them - to normalbuminruia. In patients with baseline proteinuria changes of albuminuria were not significant.
Results. Sulodexide demonstrates antiproteinuric effect in DM patients with DN

Bibliografia

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