Immunological matching in renal transplantation: clinical and prognostic significance
- Autores: Stoliar A.G1, Berdiugina O.V1, Budkar' L.N1, Klimusheva N.F1
-
Afiliações:
- Edição: Nº 2 (2013)
- Páginas: 34-37
- Seção: Articles
- URL: https://journals.eco-vector.com/2075-3594/article/view/261742
- ID: 261742
Citar
Texto integral
Acesso aberto
Acesso está concedido
Acesso é pago ou somente para assinantes
Resumo
Aim. Estimation of influence of immunological selection of donor-recipient pair on renal allograft survival. Methods. Renal allograft survival was analyzed in 347 patients, undergone renal allotransplantation (mean age 36,98±0,60 years (12 - 58 years), 229 male, 118 female). HLA antigenes (a, b and DR-loci) were typed by serological method and genetic analysis. Results. Renal allograft survival improved in patients, in whom genetic analysis was used for selection of donor-recipient pair. Number of non-coincident antigen pairs influenced renal allograft survival, which was longest in patients with no dr loci non-coincidence. Conclusion. Immunological selection of donor-recipient pair is useful for prologation renal allograft survival.
Palavras-chave
Texto integral
Bibliografia
- Kälbe T., Alkaraz A., Budde K. et al. Трансплантация почки. Федянин М.Ю. (перевод на русский язык). Европейская ассоциация урологов, 2011. http:// www.uroweb.org/gls/pdf/russian/20_Transplantation.pdf
- Зарецкая Ю.М., Абрамов В.Ю., Мойсюк Я.Г. и др. О влиянии тканевой совместимости по HLA и некоторых других факторов на выживаемость аллотрансплантата (по результатам трансплантации трупной почки за 25 лет. Трансплантология. 2011;2-3:39-47.
- Rodriguez D.S., Jankowska-Gan E., Haynes L.D. et al. Immune regulation and graft survival in kidney transplant recipients are both enhanced by human leukocyte antigen matching. Am J Transplant. 2004; 4(4):537—543.
- Danovitch G.M., Cecka J.M. Allocation of deceased donor kidneys: past, present, and future. Am J Kidney Dis. 2003;42(5):882—890.
- Shoskes D.A., Cecka J.M. Effect of delayed graft function on short- and longterm kidney graft survival. In Terasaki P. (ed.) Clinical Transplantts 1997. Los Angeles: UCLA Tissue Typing Laboratory, 1997:297.
- Gjertson D.W. Impact of delayed graft function and acute rejection on kidney graft survival. In: Cecka J.M, Terasaki P. (eds.) Clinical Transplants. UCLA Tissue Typing Laboratory; 2000; 467.
- Koyama H., Cecka J.M. Rejection episodes. In: Cecka J.M. (ed.) Clinical Transplantts 1992. Los Angeles: UCLA Tissue Typing Laboratory 1993:391.
- Gjertson D.W. Look-up survival- tables for renal transplantation. In Terasaki P. (ed.) Clinical Transplantts 1997. Los Angeles: UCLA Tissue Typing Laboratory 1998:337.
- Gjertson D.W. The role of death in kidney graft failure. In Terasaki P. (ed.) Clinical Transplantts 1998. Los Angeles: UCLA Tissue Typing Laboratory, 1998:399.
- Зарецкая Ю.М. Клиническая иммуногенетика. М.: Медицина, 1983, 208 с. 11.
- Opelz G., Wujciak T., Döhler B. et al. HLA compatibility and organ transplant survival. Collaborative Transplant Study. Rev Immunogenet. 1999; 1(3):334—342.
- CTS Collaborative Transplant Study. http://ctstransplant.org/protected/ dataR/html_all/K-21111-0207.html
- UNOS United Network for Organ Sharing. http://www.unos.org/
Arquivos suplementares
