Features of intrarenal blood flow in patients with chronic obstructive pulmonary disease


如何引用文章

全文:

开放存取 开放存取
受限制的访问 ##reader.subscriptionAccessGranted##
受限制的访问 订阅或者付费存取

详细

Purpose. The evaluation of features of intrarenal blood flow in COPD patients by Doppler ultrasonography; evaluation of the diagnostic value of some of its parameters in relationship with the main clinical and laboratory markers of renal dysfunction. Material and Methods. The study included і98 COPD patients treated in SBHCI RCH № 2 of MHKT, and 28 healthy volunteers. All patients underwent renal ultrasound and dopplerographic examination of renal blood flow at the renal artery orifice, segmental, interlobar and arcuate arteries with the calculation of Pourcelot resistance index (Ri), as well as laboratory testing of renal function: calculation of GRFCKD-EPI, determination of serum CYSTATIN С levels, and urinary excretion of albumin and ß2-MICROGLOBULIN. Results. Correlation relationship between ri and laboratory parameters of renal dysfunction, as well as the frequency of exacerbations and renal vascular resistance was revealed. ri of arcuate artery had the greatest sensitivity and specificity for early diagnosis of nephropathy in patients with COPD. Conclusion. The results of our study allow suggest ri measurement of the renal arteries in patients with COPD as appropriate. This is due to the fact that the resistance of the renal blood flow not only reflects the presence of renal dysfunction at the preclinical stage, but also allows to evaluate the possibility of its progression.

全文:

受限制的访问

参考

  1. Смирнов А.В., Шилов Е.М., Добронравов В.А., Каюков И.Г., Бобкова И.Н., Швецов М.Ю., Цыгин А.Н., Шутов А.М. Национальные рекомендации. Хроническая болезнь почек: основные принципы скрининга, диагностики, профилактики и подходы к лечению. Клиническая нефрология. 2012;4:4-26.
  2. Митьков В.В. Практическое руководство по ультразвуковой диагностике. Общая ультразвуковая диагностика. М.: ВИДАР, 2011.
  3. Глазун Л.О., Полухина Е.В. Ультразвуковая диагностика заболеваний почек. М.: ВИДАР, 2014.
  4. Naesens M., Heylen L., Lerut E., Claes K., De Wever L., Claus F., Oyen R., Kuypers D., Evenepoel P., Bammens B., Sprangers B., Meijers B., Pirenne J., Monbaliu D., de Jonge H., Metalidis C., De Vusser K., Vanrenterghem Y. Intrarenal resistive index after renal transplantation. N. Engl. J. Med. 2013;369:1797-1806.
  5. Крутиков Е.С., Чистякова С.И., Цветков В.А. Особенности внутрипочечного кровотока у больных эссенциальной артериальной гипертензией в доклинической стадии нефропатии. Клиническая нефрология. 2015;5-6:18-22.
  6. Le Dorze M., Bouglé A., Deruddre S., Duranteau J. Renal Doppler ultrasound: a new tool to assess renal perfusion in critical illness. Shock. 2012;37:360-365.
  7. Ponte B., Pruijm M., Ackermann D., Vuistiner P., Eisenberger U., Guessous I., Rousson V., Mohaupt M.G., Alwan H., Ehret G., Pechere-Bertschi A., Paccaud F., Staessen J.A., Vogt B., Burnier M., Martin P.Y., Bochud M. Reference values and factors associated with renal resistive index in a family-based population study. Hypertension. 2014;63:136-142.
  8. Briet M., Boutouyrie P., Laurent S., London G.M. Arterial stiffness and pulse pressure in CKD and ESRD. Kidney Int. 2012;82:388-400.
  9. Okura T., Kurata M., Irita J., Enomoto D., Jotoku M., Nagao T., Koresawa M., Kojima S., Hamano Y., Mashiba S., Miyoshi K., Higaki J. Renal resistance index is a marker of future renal dysfunction in patients with essential hypertension. J. Nephrol. 2010;23:175-180.
  10. Choudhury G., Rabinovich R., MacNee W. Comorbidities and systemic effects of chronic obstructive pulmonary disease. Clin. Chest Med. 2014; 35(1):101-130.
  11. van Gestel Y.R., Chonchol M., Hoeks S.E., Welten G.M., Stam H., Mertens F.W., van Domburg R.T., Poldermans D. Association between chronic obstructive pulmonary disease and chronic kidney disease in vascular surgery patients. Nephrol. Dial. Transplant. 2010;24(9):2763-2767.
  12. Man W.D., Kemp P., Moxham J., Polkey M.I. Skeletal muscle dysfunction in COPD: clinical and laboratory observations. Clin. Sci (Lond). 2010;117(7):251-264.
  13. Болотова Е.В., Дудникова А.В. Особенности дисфункции почек у пациентов с хронической обструктивной болезнью легких. Клиническая нефрология. 2015;2-3:27-32.
  14. Report GOLD: Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. URL: http://www.goldcopd.org
  15. Zeng X., Hossain D., Bostwick D.G., Herrera G.A., Ballester B., Zhang P.L. Urinary ß 2-microglobulin is a sensitive indicator for renal tubular injury. SAJ of Case Reports. 2014;1(1):1-6.
  16. KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int. Suppl. 2013;84(3):622-623.
  17. Terada N., Ichioka K., Matsuta Y., Okubo K., Yoshimura K., Arai Y. The natural history of simple renal cysts. J. Urol. 2002;167:21-23.
  18. Sugiura T., Wada A. Resistive index predicts renal prognosis in chronic kidney disease: results of a 4-year follow-up. Clin. Exp. Nephrol. 2011; 15:114-120.
  19. Doi Y., Iwashima Y., Yoshihara F., Kamide K., Takata H., Fujii T., Kubota Y., Nakamura S., Horio T., Kawano Y. Association of renal resistive index with target organ damage in essential hypertension. Am. J. Hypertens. 2012;25:1292-1298.
  20. Hashimoto J., Ito S. Central pulse pressure and aortic stiffness determine renal hemodynamics: pathophysiological implication for microalbuminuria in hypertension. Hypertension. 2011;58:839-846.
  21. Namikoshi T., Fujimoto S., Yorimitsu D., Ihoriya C., Fujimoto Y., Komai N., Sasaki T., Kashihara N. Relationship between vascular function indexes, renal arteriolosclerosis, and renal clinical outcomes in chronic kidney disease. Nephrology (Carlton). 2015;20(9):585-590.
  22. Bigé N., Lévy P.P., Callard P., Faintuch J.M., Chigot V., Jousselin V., Ronco P., Boffa J.J. Renal arterial resistive index is associated with severe histological changes and poor renal outcome during chronic kidney disease. BMC Nephrol. 2012;13:139-147.
  23. Lebkowska U., Janica J., Lebkowski W., Małyszko J., Lebkowski T., Leoniuk J., Sobotko-Waszczeniuk O., Gacko M. Intra-Parenchymal Renal Resistive Index Variation (IRRIV) Describes Renal Functional Reserve (RFR): Pilot Study in Healthy Volunteers. Front. Physiol. 2016;7:286-291.
  24. Овчаренко С.И. Современный подход к выбору лечения больных хронической обструктивной болезнью легких Фарматека. 2013;15:64-67.

补充文件

附件文件
动作
1. JATS XML
下载
##common.cookie##